Sort   by:  
 Page size 
TranscriptomicsHomeostatic skin contains two different subsets of resident macrophages with distinct origin and gene profile.
We have found the existence of two independent populations contributing to the skin-resident macrophage pool based on their different origin. We have analyzed their gene profile by deep-sequencing (RNA-Seq). Analysis of RNA-Seq data revealed a differential expression signature between both subsets o...
ORGANISM(S): Mus musculus 
2016-07-26 | E-GEOD-50566 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis Identifies Fn14, a TNF Superfamily Receptor Member, as a Therapeutic Target in Alcoholic Hepatitis
Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease and occurs in patients with excessive alcohol intake It is characterized by marked hepatocellular damage, steatosis and pericellular fibrosis. Patients with severe AH have a poor short-term prognosis. Unfortunately, current ...
ORGANISM(S): Homo sapiens 
2012-06-14 | E-GEOD-28619 | biostudies-arrayexpress
TranscriptomicsUnexpected roles of ATP11B in platinum resistance
Platinum compounds display clinical activity against a wide variety of solid tumors. However, resistance to these agents is a major limitation in cancer therapy. Reduced platinum uptake and increased platinum export are examples of resistance mechanisms that limit the extent of DNA damage. Here, we ...
ORGANISM(S): Homo sapiens 
2013-01-23 | E-GEOD-43694 | biostudies-arrayexpress
UnknownWhole genome analysis of Leptospira licerasiae provides insight into leptospiral evolution and pathogenicity.
Not available
S-EPMC3493377 | biostudies-literature
UnknownHit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics.
Not available
S-EPMC8329730 | biostudies-literature
UnknownEvaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents.
Not available
S-EPMC6383948 | biostudies-literature
UnknownEnfortumab Vedotin With or Without Pembrolizumab in Cisplatin-Ineligible Patients With Previously Untreated Locally Advanced or Metastatic Urothelial Cancer.
Not available
S-EPMC10852367 | biostudies-literature
UnknownLead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis.
Not available
S-EPMC8412142 | biostudies-literature
UnknownPrevalence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy.
Not available
S-EPMC5225254 | biostudies-literature
UnknownA randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress.
Not available
S-EPMC10070452 | biostudies-literature
Sort   by:  
 Page size