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ProteomicsFunctional abnormalities in iPSC-CMs generated from titin-mutated patients
Dilated cardiomyopathy (DCM), a myocardial disorder that can result in progressive heart failure and arrhythmias, is defined by ventricular chamber enlargement and dilatation, and systolic dysfunction. To decipher the basis for the cardiac pathology in titin-mutated patients, we investigated the hyp...
ORGANISM(S): Homo sapiens (Human) 
2019-04-12 | PXD010513 | Pride
Dilated cardiomyopathy (dcm)  induced pluripotent stem cell-derived (ipsc)  cardiomyocytes  titin mutation  calcium transients and contraction. 
ProteomicsSequential defects in cardiac lineage commitment and maturation cause hypoplastic left heart syndrome
Complex molecular programs in specific cell lineages govern human heart development. Hypoplastic left heart syndrome (HLHS) is the most severe congenital heart defect encompassing a spectrum of left-ventricular hypoplasia occurring in association with outflow-tract obstruction. The current clinical ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD014812 | Pride
Hypoplastic left heart syndrome 
TranscriptomicsBCL2 targeting overcomes the microenvironment-induced resistance to crizotinib in ALK+ anaplastic large cell lymphoma
Drug sensitivity assessment of two different ALCL cell lines growth with or without mouse cell line co-culture
ORGANISM(S): Homo sapiens 
2025-06-16 | E-MTAB-14526 | biostudies-arrayexpress
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