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TranscriptomicsJuvenile idiopathic arthritis: peripheral blood cells
Systemic-onset juvenile idiopathic arthritis (soJIA) is a rheumatic disease in childhood characterized by systemic symptoms and a relatively poor prognosis. The peripheral leukocytes are thought to play the pathological role of soJIA although the exact cause is still obscure. In this study, we aimed...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-8361 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for myelodysplastic syndromes (MDS) and related neoplasms
In this study, to obtain a complete registry of genetic lesions in MDS and to identify novel therapeutic targets, we performed SNP array analysis and whole exome analysis for novel mutations using high-throughput sequencing technologies. In whole exome analysis, paired CD3-positive T cells were used...
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31174 | biostudies-arrayexpress
TranscriptomicsExpression analysis of mutant U2AF35 transduced cells
In this study, to obtain the biological impact of the mutated U2AF35, HeLa and TF-1 cells were retrovirally transduced with either mock, wild-type or S34F mutant of U2AF35, and Expression array was performed. Expression analysis was performed for mock, wild-type U2AF35 or S34F mutant transduced HeLa...
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31172 | biostudies-arrayexpress
TranscriptomicsExon level expression profiling of mutant U2AF35 transduced HeLa cells
In this study, to obtain the biological impact of the mutated U2AF35, HeLa cells were retrovirally transduced with either mock, wild-type or S34F mutant of U2AF35, and Exon array was performed. Exon level analysis was performed for mock, wild-type U2AF35 or S34F mutant transduced HeLa in triplicate.
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31171 | biostudies-arrayexpress
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