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GenomicsComparison of expression profiles of WT and Nrf2AY/AY mutant macrophages under electrophilic stress agent [ChIP-Seq]
Nrf2(A502Y) mutant macrophages Nrf2(AY/AY) macrophages were more susceptible to toxicity of xenobiotics. To confirm preferences of binding sequences of Nrf2 and Nrf2A502Y in vivo, we performed ChIP-Seq analyses using an anti-Nrf2 antibody on the DEM-treated peritoneal macrophages derived from Nrf2+/...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-75175 | biostudies-arrayexpress
Proteomics2H-Thiopyran-2-Thione Sulfine, a Compound For Converting H2S to HSOH/H2S2 and Increasing Intracellular Sulfane Sulfur Levels
Reactive sulfane sulfur species such as persulfides (RSSH) and H2S2 are important redox regulators and closely linked to H2S signaling. However, the study of these species is still challenging due to their instability, high reactivity, and the lack of suitable donors to produce these species. Herein...
ORGANISM(S): Oryctolagus Cuniculus (ncbitaxon:9986) 
2024-02-07 | MSV000094034 | MassIVE
TranscriptomicsComparison of expression profiles of WT and Nrf2AY/AY mutant macrophages under electrophilic stress agent [RNA-Seq]
Nrf2(A502Y) mutant failed to recognize cis-element required for induction of Nrf2 target genes.To examine whether Nrf2(A502Y) supports expression of a distinct gene set from that supported by Nrf2, RNA-Seq analysis was performed. We compared gene expression profiles in peritoneal macrophages from Nr...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-75176 | biostudies-arrayexpress
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