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GenomicsComparison of expression profiles of WT and Nrf2AY/AY mutant macrophages under electrophilic stress agent [ChIP-Seq]
Nrf2(A502Y) mutant macrophages Nrf2(AY/AY) macrophages were more susceptible to toxicity of xenobiotics. To confirm preferences of binding sequences of Nrf2 and Nrf2A502Y in vivo, we performed ChIP-Seq analyses using an anti-Nrf2 antibody on the DEM-treated peritoneal macrophages derived from Nrf2+/...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-75175 | biostudies-arrayexpress
TranscriptomicsComparison of expression profiles of WT and Nrf2AY/AY mutant macrophages under electrophilic stress agent
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-75177 | biostudies-arrayexpress
TranscriptomicsIdentification of microRNAs involved in acute rejection and spontaneous tolerance in murine hepatic allografts
Graft acceptance without the need for immunosuppressive drugs is the ultimate goal of transplantation therapy. In murine liver transplantation, allografts are accepted across major histocompatibility antigen complex barriers without the use of immunosuppressive drugs and constitute a suitable model ...
ORGANISM(S): Mus musculus 
2014-10-21 | E-GEOD-52164 | biostudies-arrayexpress
TranscriptomicsComparison of expression profiles of WT and Nrf2AY/AY mutant macrophages under electrophilic stress agent [RNA-Seq]
Nrf2(A502Y) mutant failed to recognize cis-element required for induction of Nrf2 target genes.To examine whether Nrf2(A502Y) supports expression of a distinct gene set from that supported by Nrf2, RNA-Seq analysis was performed. We compared gene expression profiles in peritoneal macrophages from Nr...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-75176 | biostudies-arrayexpress
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