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TranscriptomicsRNAi knock down of Sox4 in a human adenoid cystic carcinoma cell line reveals that knockdown of Sox4 expression induces apoptosis
Sox4 is upregulated in adenoid cystic carcinoma (ACC). The ACC3 cell line is the most widely available cell culture model system of this tumor type. RNAi mediated knockdown of Sox4 in ACC3 cells induces apoptosis.
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-4225 | biostudies-arrayexpress
UnknownTwo novel species of Arthroderma isolated from domestic cats with dermatophytosis in the United States.
Not available
S-EPMC8808258 | biostudies-literature
UnknownDistinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity.
Not available
S-EPMC3820702 | biostudies-literature
UnknownA standards based ontological approach to information handling for use by organizations providing human tissue for research.
Not available
S-EPMC2623300 | biostudies-literature
UnknownmiR-99 family of MicroRNAs suppresses the expression of prostate-specific antigen and prostate cancer cell proliferation.
Not available
S-EPMC3523179 | biostudies-literature
TranscriptomicsGenomic Multivariate Predictors of Response to Adjuvant Chemotherapy in Ovarian Carcinoma: Predicting Platinum Resistance
Purpose: Despite advances in radical surgery and chemotherapy delivery, ovarian cancer is the most lethal gynecologic malignancy. Most of these patients are treated with platinum-based chemotherapies, but there is no biomarker model to guide their responses to these therapeutic agents. We have d...
ORGANISM(S): Homo sapiens 
2012-08-21 | E-GEOD-30161 | biostudies-arrayexpress
TranscriptomicsClinically significant copy number alterations and complex rearrangements of MYB and NFIB in adenoid cystic carcinoma of the head and neck
Using high-resolution, array-based comparative genomic hybridization (aCGH), we explored genomic alterations in 40 fresh-frozen ACC samples, the largest cohort to date, with the aims to: (1) identify recurrent CNAs in ACC; (2) identify novel candidate target genes; and (3) correlate recurrent CNAs w...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-34816 | biostudies-arrayexpress
UnknownIntegrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter.
Not available
S-EPMC5161754 | biostudies-literature
GenomicsGenetic and epigenetic characterization of adenoid cystic carcinoma
Translocation events are frequent in cancer and may create chimeric fusions or regulatory rearrangements that drive oncogene overexpression. Although regulatory rearrangements are increasingly recognized in hematopoietic and even solid tumors, the underlying mechanisms remain obscure. Here we identi...
EGAS00001001457 | EGA
ProteomicsProteogenomic analysis of lung adenocarcinoma reveals tumor heterogeneity, survival determinants and therapeutically-relevant pathways
To characterize the etiology of lung adenocarcinoma (LUAD) in the United States, we performed deep proteogenomic profiling of 87 tumors integrating whole genome sequencing, transcriptome sequencing, proteomics and phosphoproteomics by mass spectrometry and reverse phase protein arrays. Somatic genom...
ORGANISM(S): Homo sapiens (Human) 
2022-11-16 | PXD036025 | Pride
Apollo Lung adenocarcinoma 
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