Sort   by:  
 Page size 
TranscriptomicsSIRT6 regulates glucose metabolism and glutamatergic synapse in the mouse retina
Microarray analysis on total retinal RNA from 15 day old Sirt6 wild-type (WT) and knock-out (KO) mice. The retina is one of the major energy consuming tissues within the body. In this context, synaptic transmission between light-excited rod photoreceptors and downstream ON-bipolar neurons is a highl...
ORGANISM(S): Mus musculus 
2014-07-30 | E-GEOD-56563 | biostudies-arrayexpress
TranscriptomicsExpression array from SIRT6WT and SIRT6KO muscle
SIRT6 is a member of a highly conserved family of NAD+-dependent deacetylases with various roles in metabolism, stress resistance, and life span. SIRT6- deficient mice develop normally but succumb to a lethal hypoglycemia early in life; however, the mechanism underlying this hypoglycemia remained un...
ORGANISM(S): Mus musculus 
2015-04-12 | E-GEOD-67780 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse neocortex to investigate age-related gene expression changes
Aging is associated with major nuclear changes affecting genomic integrity and gene expression. Here we compare the gene expression profiles in the neocortex of young (5 months old) and old (30 months old) B6xC3 F1 mice. In a related study, we compare genes that change expression with age to SIRT1 a...
ORGANISM(S): Mus musculus 
2009-01-13 | E-GEOD-13120 | biostudies-arrayexpress
Sort   by:  
 Page size