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UnknownMolecular mechanisms of cell death in neurological diseases.
Not available
S-EPMC8257776 | biostudies-literature
UnknownCotargeting BCL-2 and MCL-1 in high-risk B-ALL.
Not available
S-EPMC7322969 | biostudies-literature
UnknownCombining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia.
Not available
S-EPMC6484700 | biostudies-literature
UnknownMitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming.
Not available
S-EPMC4198042 | biostudies-literature
UnknownTAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL.
Not available
S-EPMC2797639 | biostudies-literature
UnknownThe necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis.
Not available
S-EPMC7843594 | biostudies-literature
UnknownIntact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias.
Not available
S-EPMC8138548 | biostudies-literature
UnknownKinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.
Not available
S-EPMC3694067 | biostudies-literature
UnknownBH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells.
Not available
S-EPMC9287558 | biostudies-literature
UnknownCREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)-mediated apoptosis.
Not available
S-EPMC3679460 | biostudies-literature
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