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TranscriptomicsGlobal transcriptome changes in perennial ryegrass during early infection by pink snow mould
Lack of resistance to pink snow mould (Microdochium nivale) is seen as a major constraint for adaptation of perennial ryegrass (Lolium perenne L.) at higher latitudes. Plants generally become more resistant to snow moulds after cold acclimation, and almost all investigations of genetic variation in ...
ORGANISM(S): Lolium perenne 
2016-04-29 | E-MTAB-4459 | biostudies-arrayexpress
TranscriptomicsThe transcriptional repressor Blimp1/Prdm1 regulates post-natal reprogramming of intestinal enterocytes
Expression profiling of Prdm1 mutant E18.5 small intestine was performed using Illumina whole genome V2 arrays. The hypothesis tested in the present study was that Blimp1 regulates the transcription of key genes involved in enterocyte differentiation and survival. Results identify substantial and pr...
ORGANISM(S): Mus musculus 
2011-06-02 | E-GEOD-29658 | biostudies-arrayexpress
GenomicsAnalysis of Blimp-1 and Irf-1 genomic binding in wild type and Prdm1/Blimp-1 mutant embryonic gut
The goal of this study was to profile Blimp1 binding in E18.5 small intestine using a Blimp-1-eGFP knock-in allele, and to compare Blimp-1-eGFP genomic binding with Irf-1 genomic binding in normal small intestine. Changes in Irf-1 binding between wild type and Prdm1/Blimp-1 mutant small intestine w...
ORGANISM(S): Mus musculus 
2015-07-10 | E-GEOD-66069 | biostudies-arrayexpress
TranscriptomicsGenome wide RNA-seq analysis of E9.5 Smchd1 wild type and mutant embryos
We report the deregulation of expression in E9.5 male mouse embryos are that homozygous for a mutant allele of the Smchd1 gene (ie Smchd1MommeD1/MommeD1). RNA-seq analysis of Smchd1+/+ vs Smchd1MommeD1/MommeD1
ORGANISM(S): Mus musculus 
2013-07-03 | E-GEOD-44665 | biostudies-arrayexpress
TranscriptomicsGenome wide RNA-seq analysis of E14.5 Smchd1 wild type and mutant placenta
We report the deregulation of expression in Fi (C57Bl6/J x FVB/n) E14.5 male mouse placenta are that homozygous for a mutant allele of the Smchd1 gene (ie Smchd1MommeD1/MommeD1). RNA-seq analysis of Smchd1+/+ vs Smchd1MommeD1/MommeD1
ORGANISM(S): Mus musculus 
2013-07-03 | E-GEOD-44668 | biostudies-arrayexpress
TranscriptomicsBlimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta
Expression profiling of Prdm1 mutant E9.5 placenta was performed using Illumina whole genome V2 arrays. The hypothesis tested in the present study was that Blimp1 regulates the transcription of key genes involved in trophoblast differentiation. We demonstrate that the invading SpA-TGCs display robus...
ORGANISM(S): Mus musculus 
2012-07-23 | E-GEOD-39584 | biostudies-arrayexpress
TranscriptomicsSmchd1 regulates autosomal genes subject to monoallelic expression
Analysis of the genes that escape silencing in the MommeD1 allele of Smchd1 Total RNA from E9.5 embryos compared in a two factor design - gender and Smchd1 genotype
ORGANISM(S): Mus musculus 
2013-07-03 | E-GEOD-44958 | biostudies-arrayexpress
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