Mouly Vincent V

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RNA-Seq of human skeletal muscle cell line AB1167, with groups of PRDX2 KD, treated with electrical stimulation and both 2.5 and 5uM H202 for 15 minutes

This study investigates the role of peroxiredoxin 2 (PRDX2) in mediating oxidative adaptations in human skeletal muscle myotubes subjected to mechanical contraction and hydrogen peroxide (H2O2) exposure. additionally, the effect of an electrical stimulation protocol was assessed pre and post PRDX2 K...

ORGANISM(S): Homo sapiens

2025-01-01 | E-MTAB-14577 | biostudies-arrayexpress

Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres

Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disorder characterized by ptosis, dysphagia and proximal limb weakness. Autosomal-dominant OPMD is caused by a short (GCG)8–13 expansions within the first exon of the poly(A)-binding protein nuclear 1 gene (PABPN1), leading to an expanded p...

ORGANISM(S): Mus musculus

2011-01-14 | E-GEOD-26604 | biostudies-arrayexpress

White blood count, D-dimers, and ferritin levels as predictive factors of pulmonary embolism suspected upon admission in noncritically ill COVID-19 patients: The French multicenter CLOTVID retrospective study.

Not available

S-EPMC8239942 | biostudies-literature

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.

Not available

S-EPMC8532080 | biostudies-literature

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection.

Not available

S-EPMC11215417 | biostudies-literature

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.