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ProteomicsInteractome of Ca2+-bound secretagogin in mouse embryonic (E13.5) pancreas
By using His6-tagged recombinant human secretagogin in the presence of Ca2+ (100 µM), we isolated its putative interacting partners from mouse embryonic (E13.5) pancreata and identified their amino acid sequences by mass spectrometry. Next to previously described interacting partners (participating ...
ORGANISM(S): Mus musculus (Mouse) 
2018-06-13 | PXD009516 | Pride
His6-tagged recombinant secretagogin Mouse embryonic (e13.5) pancreas Pull down Protein-protein interactions 
GenomicsGene expression analysis of E13.5 Prox1-deficient mouse embryonic pancreas
Gene expression analysis of E13.5 Prox1-deficient mouse embryonic pancreas
PRJNA737506 | ENA
TranscriptomicsEffect of Bicaudal C1 deletion on E13.5 mouse pancreatic mRNA profile
Bicaudal C1 KO embryonic pancreas develops cysts and has less endocrine progenitors after E14.5 (14.5 days after fertilization), while no defect is observed at E13.5. Bicaudal C1 is an RNA-binding protein. To understand the molecular mechanisms leading to both phenotypes, the mRNA expression profile...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-58833 | biostudies-arrayexpress
GenomicsSingle-cell transcriptomics of the embryonic mouse pancreas
Single-cell transcriptomics of the embryonic mouse pancreas
PRJNA549972 | ENA
TranscriptomicsGene expression analysis of E13.5 Prox1-deficient mouse embryonic pancreas
RNA sequencing was used to identify gene expression changes in the pancreas of E13.5 Prox1-nullyzygous mouse embryos.
ORGANISM(S): Mus musculus 
2022-06-01 | GSE178173 | GEO
TranscriptomicsGene expression profiling of wild-type, Nkx2.2 null, NeuroD null and Nkx2.2/NeuroD double KO E13.5 pancreata
The experiment consist of 16 one channel assays for analyzing embryonic pancreas at E13. There are four replicates per condition. We are looking at differential gene expression across four mouse lines: WT, Nkx2.2, NeuroD and Nkx2.2/NeuroD double mutants at E13.5.
ORGANISM(S): Mus musculus 
2015-02-03 | E-MTAB-3350 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild type and Nkx2.2 mutant embryos at E12.5 and E13.5 to identify a transcripional program that Nkx2.2 regulation in the pancreas
The goal of this experiment was to analyze expression changes in the pancreas at embryonic days 12.5 and 13.5 between wild type and Nkx2.2 null mice. We know that Nkx2.2 is essential for pancreatic endocrine differentiation and development. At these early time points which are critical for endocri...
ORGANISM(S): Mus musculus 
2009-11-05 | E-CBIL-44 | biostudies-arrayexpress
TranscriptomicsIMP2/IGF2BP2 HITS-CLIP from E13.5 mouse brain
HITS-CLIP is performed for the RNA-binding protein, IMP2/IGF2BP2, from E13.5 mouse brain.
ORGANISM(S): Mus musculus 
2016-06-06 | E-MTAB-3636 | biostudies-arrayexpress
GenomicsBivalent Chromatin Marks Developmental Regulatory Genes in the Mouse Embryonic Germline in Vivo
We developed a ChIP protocol for the analysis of histone marks using less than 10,000 cells per IP, and used it to investigate the chromatin state of E11.5 mouse primordial germ cells (PGCs). A genome-wide ChIP-Seq analysis of E11.5 PGCs revealed a distribution of H3K4me3/H3K27me3 bivalent domains h...
ORGANISM(S): Mus musculus 
2013-05-30 | E-GEOD-46396 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Ngn3-expressing pancreatic cells in a time series through embryonic development and adult islet cells
Neurogenin3 (Ngn3) is a basic helix-loop-helix transcription factor which is expressed in scattered cells in the embryonic pancreas. Mice deficient for Ngn3 fail to produce any pancreatic endocrine cells and die shortly after birth. Expression of transcription factors critical to pancreatic develop...
ORGANISM(S): Mus musculus 
2007-12-15 | E-CBIL-40 | biostudies-arrayexpress
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