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TranscriptomicsPneumonia infection, lung and liver inflammation
Vaccination reduces morbidity and mortality from pneumonia but its effect on the tissue-level response to infection is still poorly understood. We evaluated pneumonia disease progression, acute phase response and lung gene expression profiles in mice inoculated intranasally with virulent gram-positi...
ORGANISM(S): Mus musculus 
2013-03-29 | E-GEOD-45644 | biostudies-arrayexpress
GenomicsMouse ear tissue at 21 days post immunization
Mouse ear tissue at 21 days post immunization
PRJNA962928 | ENA
GenomicsMouse ear tissue at 7 days post immunization
Mouse ear tissue at 7 days post immunization
PRJNA962929 | ENA
GenomicsMouse ear tissue at 2 days post immunization
Mouse ear tissue at 2 days post immunization
PRJNA962919 | ENA
GenomicsImmunization Induces Inflammation in the Mouse Heart during Spaceflight
Immunization Induces Inflammation in the Mouse Heart during Spaceflight
PRJNA1117072 | ENA
TranscriptomicsGene expression by antigen activated OT-I T cells in vivo in the presence and absence of IL-2
Much is known concerning the cellular and molecular basis for CD8+ T memory immune responses. Nevertheless, conditions that selectively support memory generation have remained elusive. Here we show that an immunization regimen that delivers TCR signals through a defined antigenic peptide, inflammato...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-39110 | biostudies-arrayexpress
TranscriptomicsSingle-cell profiling (scRNA-seq with paired V(D)J) of the splenic response to VLP immunization in MZB KO versus wild-type mice
The precise role of Marginal Zone B (MZB) cells in shaping the adaptive immune response to virus-like particle (VLP) immunization remains incompletely defined. Here, we combined VLP immunization of wild-type and MZB-deficient mice with single-cell RNA sequencing (scRNA-seq) and paired TCR/BCR profil...
ORGANISM(S): Mus musculus 
2026-01-01 | E-MTAB-16268 | biostudies-arrayexpress
ProteomicsIntegrating antigen capturing nanoparticles and type 1 conventional dendritic cell therapy for in situ cancer immunization
Eliciting a robust immune response against tumors is often hampered by the inadequate presence of effective antigen presenting cells and their suboptimal ability to present antigens within the immunosuppressive tumor microenvironment. Here, we report a cascade antigen relay strategy integrating anti...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-03 | PXD062399 | Pride
Antigen Cancer Orbitrap Mouse 
TranscriptomicsSingle cell RNA-seq of sorted Tfh cells from C57BL/6 Foxp3-GFP mice immunized with OVA-IFA and OVA-CpG
The aim of the project was the identification of the transcriptional signature of Tfh cells that emerge following immunization with different adjuvants. For this purpose C57Bl/6 mice, bearing a Foxp3-GFP reporter system, were immunized with OVA-IFA or OVA-CpG. At day 11 post-immunization, Foxp3 nega...
ORGANISM(S): Mus musculus 
2023-07-31 | E-MTAB-12085 | biostudies-arrayexpress
GenomicsRNA-sequencing of NALT from mouse after intranasal immunization with B. abortus rMDH loaded chitosan nanoparticles (CNs)
RNA-sequencing of NALT from mouse after intranasal immunization with B. abortus rMDH loaded chitosan nanoparticles (CNs)
PRJNA517469 | ENA
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