Sort   by:  
 Page size 
UnknownMyD88 and TLR4 Expression in Epithelial Ovarian Cancer.

Objective

To evaluate myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 (TLR4) expression in relation to clinical features of epithelial ovarian cancer, histologic subtypes, and overall survival.

Patients and methods

We conducted centralized immunohisto...
S-EPMC5870793 | biostudies-literature
UnknownCopy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.

Background

Known risk alleles for epithelial ovarian cancer (EOC) account for approximately 40% of the heritability for EOC. Copy number variants (CNVs) have not been investigated as EOC risk alleles in a large population cohort.

Methods

Single nucleotide polymorphism array data from ...
S-EPMC9949586 | biostudies-literature
UnknownIdentification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized that variants in the 3' untranslated region at putative microRNA (miRNA)-binding sites represent funct...
S-EPMC3709460 | biostudies-literature
UnknownEpigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with epithelial ovarian cancer risk according to histological subtype. Here we com...
S-EPMC3848248 | biostudies-literature
Sort   by:  
 Page size