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TranscriptomicsRNAi - MBD2 - MRC5 cells
Relationship between MBD2 depletion and gene expression in a normal human fibroblastic cell line, MRC5
ORGANISM(S): Homo sapiens 
2011-09-16 | E-MEXP-2916 | biostudies-arrayexpress
TranscriptomicsExpression profiling of MRC5 senescent fibroblasts
Microarrays analysis identifies WNT16in senescent fibroblasts. To identify genes expressed in replicative senescence, microarray experiments were conducted in which we compared the RNA expression profile of young MRC5 fibroblasts at population doubling 28 (PDL28) and replicative senescent MRC5 fibro...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15919 | biostudies-arrayexpress
TranscriptomicsGenomic anchors across the MHC of MRC5 cells upon treatment with IFN-gamma: Loop associated DNA vs Matrix associated DNA
Identification of genomic anchors across the MHC in untreated MRC5 fibroblasts, and fibroblasts treated with IFN-gamma, using high resolution microarrays. Identification of genomic anchors using MRC5 fibroblasts, and fibroblasts treated with IFN-gamma: Loop associated DNA vs Matrix associated DNA, 2...
ORGANISM(S): Homo sapiens 
2012-02-16 | E-GEOD-35845 | biostudies-arrayexpress
TranscriptomicsIllumina Microarray of MRC5 cell with or without KDM7A-DT overexpression
KDM7A Divergent Transcript (KDM7A-DT) is a stress-induced lncRNAs. In our previous studies, KDM7A-DT showed the most robust cellular phenotype alteration and a significant TP53-dependency upon oxidative and oncogenic stress induction. To investigate the functional roles of KDM7A-DT, we first perform...
ORGANISM(S): Homo sapiens 
2023-05-01 | E-MTAB-11819 | biostudies-arrayexpress
GenomicsTranscriptome of MRC5 fibroblasts
Transcriptome of MRC5 fibroblasts
PRJNA719841 | ENA
TranscriptomicsTranscription profiling of human MRC5, IFN gamma treated MRC5 and PGF cells.
Expression profiling of MRC5, IFN gamma treated MRC5 and PGF cells. Experiment Overall Design: MRC5 cells were treated for 24 hours with IFN gamma (200 IU/ml) and their expression profile was compared to untreated MRC5 and PGF cells.
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-10880 | biostudies-arrayexpress
GenomicsChIP-seq in MRC5 hIPSCs overexpressing MEG3 RNA.
This experiment was designed to detect differences in PRC2 occupancy in a human induced pluripotent cell line (MRC5) naturally deficient in MEG3 RNA after lentiviral overexpression of MEG3. MRC5 were transduced with lentiviruses for the overexpression of MEG3 lncRNA or GFP as a control. ChIP-seq was...
ORGANISM(S): Homo sapiens 
2013-12-25 | E-GEOD-48515 | biostudies-arrayexpress
TranscriptomicsGenomic alteration in MRC5-derived induced pluripotent stem (MRC5-iPS) cell line, Tic
Disease-specific induced pluripotent stem (iPS) cells have been used for a model to analyze pathogenesis of the disease. We generated iPS cells derived from a fibroblastic cell line of ataxia telangiectasia (AT-iPS cells). In analysis of AT-iPS cells, the human wild-type iPS cell line (MRC5-iPS) was...
ORGANISM(S): Homo sapiens 
2013-07-23 | E-GEOD-49082 | biostudies-arrayexpress
TranscriptomicsHIF2A(EPAS1) Genome-Wide Localization in MRC5 Human Fibroblasts by Cut & Tag
HIF2A(EPAS1) geenome_wide localization by Cut & Tag in MRC5 human fibroblasts ectopically expressing HIF2A in the pBabe vector, and in control MRC5 human fibroblasts containing only the pBabe vector. 2 biological replicates were done for the MRC5-HIF2A cells. Cut & Tag with an anti-H3-K27me3 Ab was ...
ORGANISM(S): Homo sapiens 
2025-01-17 | E-MTAB-13732 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of influenza A/Puerto Rico/8/1934 (H1N1) virus infected MRC5, WI-38 VA-13, A549 and HEK293FT human cells
To study genes involved in cellular response to Influenza A virus infection, human cells MRC5, WI-38 VA-13, A549 and HEK293FT were infected with influenza A/Puerto Rico/8/1934 (H1N1) virus. RNA-seq analysis of infected cell lines after 48 h was performed on an Illumina NextSeq 500 platform. The same...
ORGANISM(S): Homo sapiens 
2020-11-23 | E-MTAB-9511 | biostudies-arrayexpress
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