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GenomicsMethylation dynamics of mouse neuron by MeDIP-seq and MRE-seq
Study DNA methylation of mouse neuron using MeDIP-seq and MRE-seq DNA methylation of mouse neuron using MeDIP-seq and MRE-seq
ORGANISM(S): Mus musculus 
2015-02-20 | E-GEOD-53694 | biostudies-arrayexpress
GenomicsTranscriptional profile of MRE deficient BLaER1 monocytes [RNA MRE]
Transcriptional profile of MRE deficient BLaER1 monocytes [RNA MRE]
PRJNA757712 | ENA
TranscriptomicsTranscriptional profile of MRE deficient BLaER1 monocytes [RNA MRE]
We have identified a MORC3-regulated DNA element (MRE) that regulates the activation of IFNB1 upon loss of MORC3. To study the global transcriptional effects of the MRE, we deleted the MRE in STAT1–/– STAT2–/– and STAT1–/– STAT2–/– MORC3–/– BLaER1 monocytes and performed RNA-seq.
ORGANISM(S): Homo sapiens 
2021-11-01 | GSE182753 | GEO
GenomicsComparative DNA methylome analysis of endometrioid adenocarcinoma, uterine papillary serous carcinoma, and normal endometrium
Classically, there are two types of endometrial cancer, endometrioid adenocarcinoma (EAC), or Type I; and uterine papillary serous carcinoma (UPSC), or Type II. These two types of cancers exhibit distinct DNA methylation levels in promoters of many genes. In EAC, many tumor suppressor genes were sil...
ORGANISM(S): Homo sapiens 
2014-10-12 | E-GEOD-51565 | biostudies-arrayexpress
GenomicsCapture MRE-seq for methylation analysis of highly degraded DNA samples
Capture MRE-seq for methylation analysis of highly degraded DNA samples
PRJNA656241 | ENA
GenomicsDevelopmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos (MRE-seq)
DNA methylation undergoes dynamic changes during development and cell differentiation. Recent genome-wide studies discovered that tissue-specific differentially methylated regions (DMRs) often overlap tissue-specific distal cis-regulatory elements. However, developmental DNA methylation dynamics of ...
ORGANISM(S): Danio rerio 
2015-02-13 | E-GEOD-52704 | biostudies-arrayexpress
UnknownRistretto MRE: A generalized multi-shot GRE-MRE sequence.
Not available
S-EPMC6590281 | biostudies-literature
GenomicsWidespread contribution of transposable elements to the innovation of gene regulatory networks [human ENCODE]
Transposable elements (TE) have been shown to contrain functional transcription factor (TF) binding sites for long, but the extent to which TEs contribute TF binding sites is not well know. Here, we comprehensively mapped binding sites for 26 pairs of orthologous TFs, in two pairs of human and mouse...
ORGANISM(S): Homo sapiens 
2014-05-09 | E-GEOD-56774 | biostudies-arrayexpress
GenomicsWidespread contribution of transposable elements to the innovation of gene regulatory networks [mouse ENCODE]
Transposable elements (TE) have been shown to contrain functional transcription factor (TF) binding sites for long, but the extent to which TEs contribute TF binding sites is not well know. Here, we comprehensively mapped binding sites for 26 pairs of orthologous TFs, in two pairs of human and mouse...
ORGANISM(S): Mus musculus 
2014-05-09 | E-GEOD-57230 | biostudies-arrayexpress
GenomicsGenome-wide maps of cytosine methylation, cytosine hydroxylmethylation and small non coding RNAs in mouse ES cells and upon guided differentiation to mesoendoderm cells
Genome-wide maps of cytosine methylation, cytosine hydroxylmethylation and small non coding RNAs in mouse ES cells and upon guided differentiation to mesoendoderm cells. Mouse embryonic stem cells (E14) were guided differentiated into mesoendoderm lineages by activin-A induction. cells in three time...
ORGANISM(S): Mus musculus 
2012-09-22 | E-GEOD-38596 | biostudies-arrayexpress
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