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TranscriptomicsMRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development
Chemokine signaling is important for the seeding of different sites by hematopoietic stem cells during development. Serum Response Factor (SRF) controls multiple genes governing adhesion and migration, mainly by recruiting members of the Myocardin-Related Transcription Factor (MRTF) family of G-acti...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-63820 | biostudies-arrayexpress
TranscriptomicsExpression data from MRTFA-B double knockout brain
We used microarrays to detail the global pattern of gene expression in the cortical regional of MRTF-A/-B double knockout mice at Postnatal day 0 (P0). RNA samples were collected from the cortical regions of control and MRTF-A/-B double knockout mice at P0. Three control MRTFA-/-;MRTF-BFlox/Flox an...
ORGANISM(S): Mus musculus 
2010-06-16 | E-GEOD-22117 | biostudies-arrayexpress
TranscriptomicsMyocardin-related Transcription Factors Are Required for Skeletal Muscle Development
Myocardin-related transcription factors (MRTFs) play a central role in the regulation of actin expression and cytoskeletal dynamics. Stimuli that promote actin polymerization allow for shuttling of MRTFs to the nucleus where they activate serum response factor (SRF), a regulator of actin and other c...
ORGANISM(S): Mus musculus 
2016-08-02 | E-GEOD-84063 | biostudies-arrayexpress
GenomicsLap2α is required for MRTF-A-SRF transcriptional activity [ChIP-seq]
Lap2α is required for MRTF-A-SRF transcriptional activity [ChIP-seq]
PRJNA668630 | ENA
GenomicsLap2α is required for MRTF-A-SRF transcriptional activity [RNA-seq]
Lap2α is required for MRTF-A-SRF transcriptional activity [RNA-seq]
PRJNA668629 | ENA
GenomicsPost-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts
Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts
PRJNA564114 | ENA
GenomicsMyocardin-related transcription factor (MRTF) mediates epithelial fibrogenesis in polycystic kidney disease
Myocardin-related transcription factor (MRTF) mediates epithelial fibrogenesis in polycystic kidney disease
PRJNA1062312 | ENA
TranscriptomicsMRTF activates TEAD-YAP target gene expression
Yes Associated Protein (YAP) and Myocardin Related Transcription Factor (MRTF) play similar roles and crosstalk in directing the transcriptional responses to chemical and physical extracellular cues. However the mechanism by which the two proteins crosstalk has been unclear. Here, we show MRTF famil...
ORGANISM(S): Homo sapiens 
2016-12-21 | GSE89182 | GEO
GenomicsMRTF-SRF signalling in the T cell IL2 response
MRTF-SRF signalling in the T cell IL2 response
PRJNA1009115 | ENA
UnknownMRTF potentiates TEAD-YAP transcriptional activity causing metastasis.
Not available
S-EPMC5694947 | biostudies-literature
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