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We used microarrays to detail the global pattern of gene expression in the cortical regional of MRTF-A/-B double knockout mice at Postnatal day 0 (P0). RNA samples were collected from the cortical regions of control and MRTF-A/-B double knockout mice at P0. Three control MRTFA-/-;MRTF-BFlox/Flox an...
ORGANISM(S): Mus musculus 
Lap2α is required for MRTF-A-SRF transcriptional activity [ChIP-seq]
Lap2α is required for MRTF-A-SRF transcriptional activity [RNA-seq]
Myocardin-related transcription factors (MRTFs) play a central role in the regulation of actin expression and cytoskeletal dynamics. Stimuli that promote actin polymerization allow for shuttling of MRTFs to the nucleus where they activate serum response factor (SRF), a regulator of actin and other c...
ORGANISM(S): Mus musculus 
Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts
MRTF-A promotes angiotensin II-induced inflammatory response and aortic dissection in mice
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity
Myocardin-related transcription factor A (MRTF-A) in complex with the serum response factor (SRF) regulates the expression of cytoskeletal genes in response to cytoplasmic and nuclear actin dynamics. Different components of nucleoskeleton, besides nuclear actin, also regulate the activity of MRTF-A....
ORGANISM(S): Mus musculus 
2020-12-15 | GSE159370 | GEO
Myocardin-related transcription factor A (MRTF-A) in complex with the serum response factor (SRF) regulates the expression of cytoskeletal genes in response to cytoplasmic and nuclear actin dynamics. Different components of nucleoskeleton, besides nuclear actin, also regulate the activity of MRTF-A....
ORGANISM(S): Mus musculus 
2020-12-15 | GSE159369 | GEO
Hypoglycemia induces metabolic reprogramming and neurodegeneration through SRF/MRTF-A activation in the brain
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