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Gene expression profiling of sarcoma cells treated with mithramycin A (MTA), nano-encapsulated MTA or MTA-analogs
This study was designed to gain insight about the mechanisms involved in the anti-tumor effects of mithramycin A (MTA) and the MTA analog EC-8042 in sarcoma cells. In addition, we also studied whether this molecular features could be influenced by the nano-encapsulation of MTA.
ORGANISM(S): Homo sapiens 
2021-03-30 | GSE161616 | GEO
Profiling of N6-methyladenosine (m6A) in Arabidopsis wild type and ABI3:MTA
N6-methyladenosine mRNA methylomes in the MTA RNAi strawberry fruits and the controls
GMUCT sequencing of 4 week old leaves in Arabidopsis ABI3:MTA plants
mRNA sequencing of 4 week old leaves in Arabidopsis wild type and ABI3:MTA
For exploring the influence of the m6A methyltransferase gene MTA silencing in the global m6A mRNA methylomes of strawberry fruits, we performed m6A-seq in the MTA RNAi strawberry fruits (RNAi-MTA) and the controls with three independently biological replicates. Results showed that MTA silencing ind...
ORGANISM(S): Fragaria x ananassa 
2021-05-20 | GSE174703 | GEO
mRNA adenosine methylase (MTA) deposits m6A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana [smallRNAs]
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