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ProteomicsComposition of Rosenthal fibers in Alexander disease patients and mouse models
Alexander disease (AxD) is a fatal neurodegenerative disorder characterized by the presence in astrocytes of protein aggregates called Rosenthal fibers (RFs). In this work, we used a new biochemical fractionation method to enrich for RFs followed by analysis of this fraction using quantitative iTRA...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2016-05-23 | PXD002448 | Pride
Alexander disease Rosenthal fibers Itraq 8-plex 
MetabolomicsIn plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (Imaging MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS769 | MetaboLights
UnknownComposition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease.
Not available
S-EPMC5036859 | biostudies-literature
UnknownNIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods.
Not available
S-EPMC6944243 | biostudies-literature
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