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TranscriptomicsTranscription profiling of human mayometrium and uterine fibroids with normal and non-normal karyotypes
Normal myometrium and uterine fibroids (partially paired from the same donor) were profiled. FISH analysis was used to analyze the karyotype of the uterine fibroid samples. This study provides further insights in the development of uterine fibroids. Additional uterine fibroid samples from the same s...
ORGANISM(S): Homo sapiens 
2023-07-01 | E-MTAB-12550 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human uterine fibroids with normal karyotype and 12q14~15 rearrangements
12q14~15 chromosomal rearrangements, specifically affecting the HMGA2 gene locus, are frequently observed in human uterine fibroids. Those fibroids are observed to show fast growth to a larger size compared to fibroids of normal karyotype. Since the HMGA2 gene is overexpressed, this study provides f...
ORGANISM(S): Homo sapiens 
2012-11-05 | E-MTAB-340 | biostudies-arrayexpress
TranscriptomicsAssessment of genotoxic effects and changes in gene expression in humans exposed to formaldehyde by inhalation under controlled conditions
41 volunteers (male non-smokers) were exposed to formaldehyde (FA) vapors for 4 h per day over a period of 5 working days under strictly controlled conditions. For each exposure day, different exposure concentrations were used in a random order ranging from 0 up to 0.7 ppm. At concentrations of 0.3 ...
ORGANISM(S): Homo sapiens 
2011-05-04 | E-GEOD-27263 | biostudies-arrayexpress
TranscriptomicsIdentification of iron regulated genes.
Identification of transcriptional changes of Ustilago maydis wild type strain FB1 grown in axenic culture in complete medium containing glucose without or with the addition of 10 µM FeSO4. Keywords: gene induction Strain FB1 (wt) was grown in CM glucose medium in the presence or absence of 10 µM F...
ORGANISM(S): Ustilago maydis 
2010-06-12 | E-GEOD-6037 | biostudies-arrayexpress
TranscriptomicsIdentification of Adr1 regulated genes
Adr1 of Ustilago maydis is a protein kinase that is activated after separation from the regulatory subunit mediated by high cAMP levels. A copy of the gene under the control of the arabinose-inducible crg1 promotor was introduced into the Cbx locus of the wild type strain FB1 creating strain HE140. ...
ORGANISM(S): Ustilago maydis 
2010-06-12 | E-GEOD-6039 | biostudies-arrayexpress
TranscriptomicsIdentification of genes regulated by the iron dependent transcription factor Urbs1.
Urbs1 of Ustilago maydis is a transcription factor that has been shown to repress its target genes (e.g. sid1, sid2) in the presence of iron. To identify additional genes regulated by Urbs1, we compared transcriptional profiles of the Ustilago maydis wild type strain FB1 grown in complete medium con...
ORGANISM(S): Ustilago maydis 
2010-06-12 | E-GEOD-6038 | biostudies-arrayexpress
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