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MetabolomicsImproving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry
Untargeted metabolomics aims at obtaining quantitative information on the highest possible number of low-molecular biomolecules present in a biological sample. Rather small changes in mass spectrometric spectrum acquisition parameters may have a significant influence on the detectabilities of metabo...
2016-06-09 | MTBLS233 | MetaboLights
UnknownThrombospondin-2 and LDH Are Putative Predictive Biomarkers for Treatment with Everolimus in Second-Line Metastatic Clear Cell Renal Cell Carcinoma (MARC-2 Study).
Not available
S-EPMC8199288 | biostudies-literature
TranscriptomicsComparative genomic hybridization by array of human brain metastases and primary breast carcinomas
This study comprises arrayCGH data from the University clinic Eppendorf (UKE) in Hamburg. The array platform being used is the VUMC v30 30k Oligo chip
ORGANISM(S): homo sapiens 
2012-03-08 | E-MTAB-354 | biostudies-arrayexpress
ProteomicsAbsolute protein quantification of Mycoplasma pneumoniae proteome by combining selected reaction monitoring of a reduced set of labeled peptides and label-free shotgun mass spectrometry.
We quantified the protein abundances of Mycoplasma pneumoniae (Mpn), a genome-reduced organism, by combining selected reaction monitoring of a reduced set of labeled peptides and label-free shotgun mass spectrometry. A set of 77 labeled peptides were synthesized and used as internal standard peptide...
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2023-08-31 | PXD035159 | Pride
Mycoplasma pneumoniae Absolute quantification Label-free Selected reaction monitoring 
ProteomicsProteomic consequences of TDA1 deficiency in Saccharomyces cerevisiae — Spot Identifications
Hexokinase 2 (Hxk2) of Saccharomyces cerevisiae is a dual function hexokinase, acting as a glycolytic enzyme and being involved in the transcriptional regulation of glucose-repressible genes. Relief from glucose repression is accompanied by phosphorylation of Hxk2 at serine 15, which has been attrib...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-03 | PXD037135 | Pride
Proteomics Hxk2 Glucose signaling Hxk1 Serine/threonine protein kinase Yeast Hexokinase Glucose metabolism Phosphorylation Ymr291w/tda1 
ProteomicsEnzymatic dissociation induces transcriptional and proteotype bias in brain cell populations
Different cell isolation techniques exist for transcriptomic and proteotype profiling of brain cells. Here we show that standard enzymatic digestion of brain tissue at 37°C induces profound alterations in the transcriptome and proteotype of specific brain cells, as compared to cold mechanical dissoc...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD015592 | Pride
Brain cell types enzymatic digestion bias isolation 
Genomicsena-DATASET-NIBR-04-08-2016-14:28:22:169-118 - samples
Exome sequencing reads of two UFM individuals and their family members (totally 11 individuals) belonging to two different Fragile X families. Alignment files in BAM format are provided.
EGAD00001002276 | EGA
GenomicsExome-sequencing of two UFM individuals and their Fragile X family members.
Fragile X syndrome (FXS) is a monogenic neurodevelopmental disease often caused by a CGG triplet expansion in the 5’UTR of the FMR1 gene, which results in DNA methylation of the FMR1 promoter and its transcriptional silencing. Exceptional healthy individuals named "unmethylated full mutation (UFM)" ...
EGAS00001001737 | EGA
GenomicsNovartis-Cattolica UFM collaboration Data Access Committee
Data Access Committee EGAC00001000512
EGAC00001000512 | EGA
TranscriptomicsSystems analysis of the response of photosynthesis, metabolism and growth to an increase in irradiance in the photosynthesis model organism Chlamydomonas reinhardtii
Systems analysis reveals that Chlamydomonas reinhardtii responds rapidly and flexibly to an increase in light intensity. Rising metabolite levels and post-translation regulation facilitate a rapid increase in the rate of carbon fixation and a slightly delayed increase in the rate of growth, and slow...
ORGANISM(S): Chlamydomonas reinhardtii 
2014-04-30 | E-GEOD-56800 | biostudies-arrayexpress
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