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TranscriptomicsRegulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling
Illumina Beadchip array analyses of mouse embryonic stem cell gene expression profiles in the presence of or upon knockdown of Aurka. An ES complementation 'rescue' system was employed to measure the effects of knockdown (minus Dox). Aurka was rescued to wildtype levels in the presence of Dox (plus ...
ORGANISM(S): Mus musculus 
2012-05-29 | E-GEOD-23541 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profile on hiPSCs and hiPSC-derived CD33+ myeloid cells
To gain insights into which pathways might be dysregulated in JMML, we compared the transcriptome profiles among hiPSC and sorted CD33+ myeloid cells from control and patient samples. NS/JMML-derived CD33+ myeloid cells showed dysregulation in major biological processes. Moreover, a consistent expre...
ORGANISM(S): Homo sapiens 
2014-01-31 | E-GEOD-54538 | biostudies-arrayexpress
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