The integration of omics technologies into molecular biological research has transformed it into a field where a system can be investigated as a whole by combining information from multiple biochemical layers. This extension of traditional molecular biology, where various data sources are conside...

Abstract This study focused on elucidating the lignocellulose degradation mechanism of Pholiota adiposa strain YAHS, aiming to provide theoretical basis and microbial resources for straw biorefining. Using the aniline blue-guaiacol plate screening method, 11 fungal strains were isolated from the ...

Huaganjian (HGJ) is a traditional Chinese medicinal formula with liver-protective effects. However, the pharmacological mechanisms of the effects of HGJ on cholestatic liver fibrosis (CLF) are yet to be clarified. To evaluate the effects of HGJ on CLF and elucidate the underlying mechanisms, C57B...

Alcohol-related brain damage (ARBD) constitutes a major global public health issue and is often comorbid with neuropsychiatric disorders such as Alzheimer's and Parkinson's diseases. Ferroptosis, a form of regulated cell death characterized by iron dependency and lipid peroxidation, has been impl...

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis.

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis

Exploring the mechanism of YJW's antidepressant effect based on multi omics analysis

Hunner-type interstitial cystitis/bladder pain syndrome (HIC) is a complex and clinically challenging chronic disorder characterized by bladder-centered symptoms, including persistent pelvic pain and urinary urgency frequency, with elusive pathogenesis involving poorly defined multi-system intera...

Hunner-type interstitial cystitis/bladder pain syndrome (HIC) is a complex and clinically challenging chronic disorder characterized by bladder-centered symptoms, including persistent pelvic pain and urinary urgency frequency, with elusive pathogenesis involving poorly defined mult...

Here, we selected Roseovarius nubinhibens as the model organism to comprehensively interrogate aromatic compound metabolism in marine Roseobacter clade. First, we preliminarily elucidated the three distinct mechanisms of aromatic compound transmembrane transport in R. nubinhibens. By integrating ...

This study employs integrated multi-omics analysis to systematically investigate the proteome and metabolome of marine bacterium Vibrio natriegens strain VCOD-2 (ATCC 14048) under optimal salinity (3% NaCl) and high-salinity stress (8% NaCl) conditions, aiming to reveal the molecular me...