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TranscriptomicsTranscription profiling of human stemic juvenile idiopathic arthritis, , systemic lupus erythematosus,, type I diabetes, metastatic melanoma, acute infections, or liver-transplant recipients undergoing immunosuppressive therapy (n = 37)
The analysis of patient blood transcriptional profiles offers a means to investigate the immunological mechanisms relevant to human diseases on a genome-wide scale. In addition, such studies provide a basis for the discovery of clinically relevant biomarker signatures. We designed a strategy for mic...
ORGANISM(S): Homo sapiens 
2008-10-04 | E-GEOD-11907 | biostudies-arrayexpress
TranscriptomicsInterferon Signature in the Blood in Inflammatory Common Variable Immune Deficiency [Test Set]
Transcriptional profiling was used to characterize the immunologic networks in subjects with CVID who have inflammatory complications to identify clues as to pathogenesis and potentially better modes of treatment. CVID subjects who fulfilled the standard diagnostic criteria, including significantly ...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-51404 | biostudies-arrayexpress
TranscriptomicsInterferon Signature in the Blood in Inflammatory Common Variable Immune Deficiency [Training Set]
Transcriptional profiling was used to characterize the immunologic networks in subjects with CVID who have inflammatory complications to identify clues as to pathogenesis and potentially better modes of treatment. CVID subjects who fulfilled the standard diagnostic criteria, including significantly ...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-51405 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human systemic lupus erythematosus patients to develop a transcriptional indicator of disease progression
Transcriptional modules were used as a basis for the selection of biomarkers and the development of a multivariate transcriptional indicator of disease progression in patients with systemic lupus erythematosus. Experiment Overall Design: The proposed biomarker-selection strategy relies on modules ...
ORGANISM(S): Homo sapiens 
2008-10-01 | E-GEOD-11909 | biostudies-arrayexpress
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