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TranscriptomicsFunctional evidence that Drosha over-expression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles [miRNA]
Comparison of miRNA expression profiles in cervical carcinoma cell lines to study the effects of Drosha expression levels Analyzed global miRNA expression profiles from 18 samples (7 samples in duplicate, 4 single sample) representing cervical carcinoma cell lines with either relative Drosha over-e...
ORGANISM(S): Homo sapiens 
2011-05-25 | E-GEOD-26175 | biostudies-arrayexpress
TranscriptomicsGain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome [camb1Mb data]
For many oncogenes, increased expression resulting from copy number gain confers a selective advantage to cells that consequently make up the tumour bulk. To identify oncogenes of potential biological significance in cervical squamous cell carcinoma (SCC), 36 primary samples and ten cell lines were ...
ORGANISM(S): Homo sapiens 
2011-02-16 | E-GEOD-27332 | biostudies-arrayexpress
TranscriptomicsGain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome [penn1Mb data]
For many oncogenes, increased expression resulting from copy number gain confers a selective advantage to cells that consequently make up the tumour bulk. To identify oncogenes of potential biological significance in cervical squamous cell carcinoma (SCC), 36 primary samples and ten cell lines were ...
ORGANISM(S): Homo sapiens 
2011-02-16 | E-GEOD-27331 | biostudies-arrayexpress
TranscriptomicsFunctional evidence that Drosha over-expression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles [mRNA]
Comparison of mRNA expression profiles in W12 Series 1 cervical ectokeratinocytes at passage number 22 versus 19 (during which time the cells gain an invasive phenotype) As these cells demonstrate gain of chromosome 5p during this time, mRNA expression profiling data interrogated for over-expressed ...
ORGANISM(S): Homo sapiens 
2011-05-25 | E-GEOD-26176 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pediatric malignant germ cell tumors
To compare the transcriptome profiles of the two principal histological variants of malignant germ cell tumor that occur in childhood Experiment Overall Design: Here, we analyzed the global gene expression profiles of 27 pediatric MGCTs from the two principal histologies (18 yolk sac tumors [YSTs] a...
ORGANISM(S): Homo sapiens 
2008-06-18 | E-GEOD-10615 | biostudies-arrayexpress
TranscriptomicsMalignant Germ Cell Tumors Display Common microRNA Profiles Resulting in Global Changes in Expression of mRNA Targets
Comparison of miRNA expression profiles in malignant germ cell tumors compared to non-malignant control group. Use of bioinformatic algorithm Sylamer to interrogate mRNA expression profiles from malignant germ cell tumors for enrichment or depletion of binding sites for differentially expressed miRN...
ORGANISM(S): Homo sapiens 
2010-03-14 | E-GEOD-18155 | biostudies-arrayexpress
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