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ProteomicsLineage-specific oncogenes drive growth of major forms of human cancer using common downstream mechanisms
Aim of the experiment was to identify changes in protein-protein interactions between proliferating and non-proliferating cells. For this purpose, RKO cells were treated with 20nM Trametinib, HCT116 with 8nM Trametinib, and NCI-H1975 100nM Osimertinib. At these concentrations, the wild type cell lin...
ORGANISM(S): Homo sapiens (Human) 
2025-07-17 | PXD037155 | Pride
Proteomics Pisa assay Protein solubility Lung cancer Proliferation Lc-ms/ms Colorectal cancer 
TranscriptomicsSingle-cell RNA-seq of human cancer cell lines and their resistant variants treated with cytostatic kinase inhibitors
Intent of the experiment was to identify common factors associated with proliferation in multiple cancer cell lines from different tissue of origin. Cell lines and their resistant variants were treated with 0, 0.8, 4, 20, 100, 500 nM drug concentration at 2, 6, 12, and 24 hour time points. Experimen...
ORGANISM(S): Homo sapiens 
2023-11-08 | E-MTAB-13427 | biostudies-arrayexpress
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