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ProteomicsProteomics profiling of research models for studying pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a five-year survival rate of 10-15% due to late-stage diagnosis and limited efficacy of existing treatments. This study utilized proteomics-based system modelling to generate multimodal datasets from various re...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-18 | PXD057795 | Pride
Murine pdac tumor 
ProteomicsProteomics profiling of research models for studying pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a five-year survival rate of 10-15% due to late-stage diagnosis and limited efficacy of existing treatments. This study utilized proteomics-based system modelling to generate multimodal datasets from various re...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-18 | PXD057793 | Pride
Murine pdac cells 
GenomicsIL-1b+ tumor-associated macrophages fuel pathogenic inflammation in pancreatic cancer - scRNA-seq of murine PDAC samples
IL-1b+ tumor-associated macrophages fuel pathogenic inflammation in pancreatic cancer - scRNA-seq of murine PDAC samples
PRJNA901010 | ENA
ProteomicsProteomics profiling of research models for studying pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a five-year survival rate of 10-15% due to late-stage diagnosis and limited efficacy of existing treatments. This study utilized proteomics-based system modelling to generate multimodal datasets from various re...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-18 | PXD057798 | Pride
Murine normal pancreatic tissue 
GenomicsCUT&Tag sequencing in PDAC cells with Setd2-KO and Setd2-WT sorted from orthotopic PDAC tumor
CUT&Tag sequencing in PDAC cells with Setd2-KO and Setd2-WT sorted from orthotopic PDAC tumor
PRJNA804002 | ENA
TranscriptomicsMurine PDAC cell lines
Expression profiles of 28 murine pancreatic cancer cell lines isolated from a KrasG12D-based mouse model of pancreatic cancer mRNA of 28 low passaged murine pancreatic cancer cell lines was extracted and hybridized to Affymetrix microarrays
ORGANISM(S): Mus musculus 
2012-09-06 | E-GEOD-40609 | biostudies-arrayexpress
TranscriptomicsTranscriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer fatalities in Western societies, characterized by high metastatic potential and resistance to chemotherapy. Critical molecular mechanisms of these phenotypical features still remain unknown, thus hampering the development ...
ORGANISM(S): Homo sapiens 
2015-06-16 | E-GEOD-59761 | biostudies-arrayexpress
GenomicsCU44_WGS of YFP+ sorted tumor cells from murine PKCY and A3A_PKCY pancreatic tumors
We aimed to decipher human APOBEC3A driven genomic differences in pancreatic tumors in vivo using a genetically engineered mouse model for pancreatic cancer. Murine pancreatic tumor formation was driven by p53fl/+;KrasLSL-G12D/+;Pdx1-Cre;Rosa26LSL-YFP (PKCY) and p53fl/+;KrasLSL-G12D/+;Pdx1-Cre; Rosa...
ORGANISM(S): Mus musculus 
2021-09-06 | E-MTAB-9843 | biostudies-arrayexpress
GenomicsGene expression profile of tumour-infiltrating immune cells in murine PDAC
Gene expression profile of tumour-infiltrating immune cells in murine PDAC
PRJNA1245301 | ENA
GenomicsCITE-seq analysis of murine subcutaneos PDAC tumor models under pan-KRAS inhibitor and/or anti-PD1 treatment combinations
CITE-seq analysis of murine subcutaneos PDAC tumor models under pan-KRAS inhibitor and/or anti-PD1 treatment combinations
PRJNA1299441 | ENA
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