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The abundance of isoforms of p73 in clinical samples is indicative for the patient's survival and the aggressiveness of the tumor, also in cell culture. On the basis of the well-etablished Sk-Mel-29 cell line model, we over-expressed two isoforms by transduction of a respective adenoviral vector.
ORGANISM(S): Homo sapiens 
All p73 isoforms share an identical DNA-binding domain. These CUT&RUN datasets for TAp73α, DNp73β, and a GFP control illustrate the isoform-specific differences in genomic binding. As no antibodies are currently available that selectively recognize individual p73 variants, the data were generated fo...
ORGANISM(S): Homo sapiens 
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