Sort   by:  
 Page size 
Identification of somatic alterations in cancer has become feasible with the massive adoption of next generation sequencing. However, due to variability in sequencing and informatics pipelines, a common somatic reference is needed. We thus performed paired whole genome sequencing of a metastatic mel...
Innate immune cells shape the host response to microbial pathogens. Here we studied the role of TLR7/9 in dendritic cell (DC) responses to Histoplasma capsulatum, an intracellular fungal pathogen of humans. Whereas macrophages succumbed to Histoplasma infection, TLR7/9 were critical for DCs to produ...
ORGANISM(S): Mus musculus 
Paired PCR-free whole genome sequencing data of a matched metastatic melanoma cell line (COLO829) and normal across three lineages and across separate institutions, with independent library preparations, sequencing, and analysis. The data was generated with mean mapped coverages of 99X for COLO829 a...
This paper describes the work by Akbari V,. et al. on detection of allele specific methylation using oxford nanopore sequencing data. They have developed set of tools, SNVoter and NanoMethPhase, and workflow which enable the detection of allele specific methylation even in samples with sparse covera...
Sort   by:  
 Page size