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MetabolomicsSkeletal muscle metabolomics and blood biochemistry analysis reveal metabolic changes associated with dietary amino acid supplementation in dairy calves
The effects of different amino acid (AA) supplementations of milk protein-based milk replacers in pre-ruminant calves from 3 days to 7 weeks of age were studied. Animals were divided into 4 groups: Ctrl) Control group fed with milk protein-based milk replacer without supplementation; GP) supplementa...
2018-10-08 | MTBLS720 | MetaboLights
MetabolomicsGenomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep
Reversal of fatty infiltration of pennate rotator cuff muscle after tendon release is hitherto impossible. The administration of nandrolone starting at the time of tendon release prevents the increase in fat content, but does not revert established fatty infiltration. We hypothesised that tendon rel...
2017-07-14 | MTBLS322 | MetaboLights
MetabolomicsAmino Acid Quantifcation of obese patients on a 16 week caloric restriction from muscle biopsy
Not available
ORGANISM(S): Homo sapiens 
ST000484 | MetabolomicsWorkbench
MetabolomicsEffect of L-carnitine administration on lipid and metabolite content in sheep infraspinatus muscle after tendon release
Metabolites and lipid species were measured using ultrahigh performance lipid chromatography – tandem mass spectrometry in biopsies of infraspinatus muscle after 2 weeks of tendon release in the operated and contralateral muscle. A group of animals received oral treatment with L-carnitine.
2020-07-20 | MTBLS1490 | MetaboLights
MetabolomicsResponse to dietary carbohydrates in European seabass (Dicentrarchus labrax) muscle tissue as revealed by NMR-based metabolomics

INTRODUCTION: Feed optimization is a key step to the environmental and economic sustainability of aquaculture, especially for carnivorous species. Plant-derived ingredients can contribute to reduce costs and nitrogenous effluents while sparing wild fish stocks. However, the metab...

2019-01-22 | MTBLS619 | MetaboLights
MetabolomicsMetabolome and proteome changes in skeletal muscle and blood of pre-weaning calves fed leucine and threonine supplemented diets

In pre-weaning calves, both leucine and threonine play important roles in growth and muscle metabolism. In this study, metabolomics, proteomics and clinical chemistry were used to assess the effects of leucine and threonine supplementation added to milk replacer on 14 newborn Holstein male calves...

2020-02-20 | MTBLS1045 | MetaboLights
MetabolomicsDelayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle

Exercise is fundamental to healthy aging, yet the degree to which it mitigates age-related molecular changes and how varying physical fitness levels influence the molecular response to exercise with age remain unclear. To address this, we performed transcriptomics, lipidomics, and metabolomics on...

2026-04-09 | MTBLS12824 | MetaboLights
TranscriptomicsDUX4-induced gene expression is the major molecular signature in FSHD skeletal muscle
Facioscapulohumeral dystrophy (FSHD) is caused by decreased epigenetic repression of the D4Z4 macrosatellite array and recent studies have shown that this results in the expression of low levels of the DUX4 mRNA in skeletal muscle. Several other mechanisms have been suggested for FSHD pathophysiolog...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-56787 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human muscle biopsies from Duchenne muscular dystrophy subjects treated with oxandrolone
Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were ...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-1764 | biostudies-arrayexpress
no omics definedTranscription profiling of skeletal muscle form patients suffering from sepsis-induced muliple organ failure
Septic patients treated in the intensive care unit (ICU) often develop multiple organ failure including persistent skeletal muscle dysfunction which results in the patient’s protracted recovery process. We have demonstrated that muscle mitochondrial enzyme activities are impaired in septic ICU pat...
ORGANISM(S): Homo sapiens 
2008-11-22 | E-GEOD-13205 | biostudies-arrayexpress
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