Muthusamy Natarajan N

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Chronic lymphocytic leukemia (1)

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Gel-based experiment (1)
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2010 (1)
2024 (1)

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Transcription profiling by array (1)

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2010 (1)
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Professor, Associate Director of Academic Affairs, Division of Hematology, Professor of Medicine, Dept of Internal Medicine (1)

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Identification of proteins that interact with Siglec-6

Siglec-6 is a glycoprotein overexpressed on chronic lymphocytic leukemia (CLL) cell. We have shown that Siglec-6 promotes migration and adhesion of CLL cells towards CLL bone marrow stromal cells. To elucidate the mechanistic pathway involved in Siglec-6 dependent migration, we performed mass spectr...

ORGANISM(S): Homo sapiens (Human)

2024-05-08 | PXD039892 | Pride

Genome-wide DNA Methylation Analysis Reveals Novel Targets for Drug Development in Mantle Cell Lymphoma

Mantle Cell Lymphoma (MCL) is a mostly incurable malignancy arising from naïve B cells (NBC) in the mantle zone of lymph node follicles. We analyzed genome-wide methylation in MCL patients using the HELP (Hpa II tiny fragment Enrichment by Ligation mediated PCR) assay and found significant aberrancy...

ORGANISM(S): Homo sapiens

2010-07-30 | E-GEOD-19243 | biostudies-arrayexpress

Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes.

Not available

S-EPMC3795457 | biostudies-literature

Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities: The I-TECH Randomized Clinical Trial.