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Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
Nitric oxide (NO) produced by macrophages (MØs) is toxic to both host tissues and invading pathogens and its regulation is therefore essential to suppress host cytotoxicity. MØ arginase 1 (Arg1) inhibits NO production by competing with NO synthases for arginine, the common substrate of NO synthases ...
ORGANISM(S): Mus musculus 
Mycobacteria
Nontuberculous mycobacteria Metagenome
Mycobacteria species Raw sequence reads
Genomes of previously unsequenced Nontubercular Mycobacteria genome sequencing
Purified NK cells were co-cultured with M. bovis BCG or M. tuberculosis H37Rv (1:1) in the presence of IL-2 (100U/ml) or IL-12 (10pg/ml) for 24h before trizol extraction. We used microarrays to detail the global gene expression underlying NK cell activation by mycobacteria. NK cell were isolated fro...
ORGANISM(S): Homo sapiens 
Temperature and pH growth preferences of nontuberculous mycobacteria - Genomic sequencing, Raw sequence reads
Non-tuberculous Mycobacteria sequencing
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