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TranscriptomicsMyocardin-related Transcription Factors Are Required for Skeletal Muscle Development
Myocardin-related transcription factors (MRTFs) play a central role in the regulation of actin expression and cytoskeletal dynamics. Stimuli that promote actin polymerization allow for shuttling of MRTFs to the nucleus where they activate serum response factor (SRF), a regulator of actin and other c...
ORGANISM(S): Mus musculus 
2016-08-02 | E-GEOD-84063 | biostudies-arrayexpress
TranscriptomicsMRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development
Chemokine signaling is important for the seeding of different sites by hematopoietic stem cells during development. Serum Response Factor (SRF) controls multiple genes governing adhesion and migration, mainly by recruiting members of the Myocardin-Related Transcription Factor (MRTF) family of G-acti...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-63820 | biostudies-arrayexpress
GenomicsMyocardin-related transcription factor (MRTF) mediates epithelial fibrogenesis in polycystic kidney disease
Myocardin-related transcription factor (MRTF) mediates epithelial fibrogenesis in polycystic kidney disease
PRJNA1062312 | ENA
UnknownA Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis.
Not available
S-EPMC4425676 | biostudies-literature
TranscriptomicsMyocardin-related transcription factor (MRTF) mediates epithelial fibrogenesis in polycystic kidney disease
Background: Autosomal dominant polycystic kidney disease (PKD) is characterized by extensive cyst formation and progressive fibrosis. However, the molecular mechanisms whereby the loss/loss-of-function of polycystin 1 or 2 (PC1/2) provokes fibrosis are largely unknown. The small GTPase RhoA has been...
ORGANISM(S): Sus scrofa 
2024-05-01 | GSE252716 | GEO
UnknownMyocardin and myocardin-related transcription factor-A synergistically mediate actin cytoskeletal-dependent inhibition of liver fibrogenesis.
Not available
S-EPMC7099496 | biostudies-literature
UnknownStress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axis.
Not available
S-EPMC4974569 | biostudies-literature
UnknownEpiregulin (EREG) and Myocardin Related Transcription Factor A (MRTF-A) Form a Feedforward Loop to Drive Hepatic Stellate Cell Activation.
Not available
S-EPMC7843934 | biostudies-literature
UnknownMyocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity.
Not available
S-EPMC5342149 | biostudies-literature
UnknownMyocardin-Related Transcription Factor A (MRTF-A) Regulates the Balance between Adipogenesis and Osteogenesis of Human Adipose Stem Cells.
Not available
S-EPMC7527895 | biostudies-literature
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