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TranscriptomicsTranscriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes
Trypanosoma cruzi infection is a major cause of cardiomyopathy. Gene profiling studies of hearts from infected mice have revealed prominent changes in gene expression within many functional pathways. This variety of transcriptomic changes in infected mice raises the question of whether gene express...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-17330 | biostudies-arrayexpress
TranscriptomicsMolecular Remodeling of Ion Channels in Human Atrial and Ventricular Myocytes Associated with Ischemic Cardiomyopathy
Ischemic cardiomyopathy (ICM) leads to congestive heart failure and can cause sudden cardiac death due to arrhythmia. Existing molecular knowledge base of ICM is rudimentary because of lack of specific attribution to cell type and function. This study was designed to investigate cell-specific molecu...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-17294 | biostudies-arrayexpress
TranscriptomicsMolecular remodeling of ion channels, exchangers and pumps in atrial and ventricular myocytes in ischemic cardiomyopathy: left ventricle DCM
We wanted to see whether the set of affected genes in ischemic cardiomyopathy (ICM) is the same or different as compared to dilated cardiomyopathy (DCM). To find this out, we placed the single DCM sample on the same microarray slide with the ICM samples. Analysis of microarray data with ICM samples ...
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-17530 | biostudies-arrayexpress
MetabolomicsEstrogen receptor α deficiency in cardiac myocytes reprograms heart-derived extracellular vesicle proteome and induces obesity in female mice (Part 1)
Not available
ORGANISM(S): Mus musculus 
ST002229 | MetabolomicsWorkbench
MetabolomicsEstrogen receptor a deficiency in cardiac myocytes reprograms heart-derived extracellular vesicle proteome and induces obesity in female mice (Part 2)
Not available
ORGANISM(S): Mus musculus 
ST002228 | MetabolomicsWorkbench
TranscriptomicsMapping the cellular and molecular landscape of cardiac non-myocytes in murine type-2 diabetes
Here we define key single-cell transcriptional alterations within cardiac non-myocytes, from ventricles of spontaneously type-2 diabetic (db/db) and control (db/h) mouse hearts ([B6.BKS(D)-Lepr/J], stock #000697). The cell preparation sequenced consisted of metabolically active, live and nucleat...
ORGANISM(S): Mus musculus 
2022-11-29 | E-MTAB-11940 | biostudies-arrayexpress
GenomicsBAIBA in human skeletal myocytes
BAIBA in human skeletal myocytes
PRJEB84181 | ENA
TranscriptomicsBAIBA in human skeletal myocytes
The metabolite beta-aminoisobutyric acid (BAIBA) as an exercise-induced muscle-derived signal regulating adipose tissue metabolism during exercise. Here, we determine that BAIBA mimics aerobic exercise training effects on human skeletal myocytes.
ORGANISM(S): Homo sapiens 
2026-06-22 | E-MTAB-14746 | biostudies-arrayexpress
GenomicsEffect of Nr2f6 knockdown in C2C12 myocytes
Effect of Nr2f6 knockdown in C2C12 myocytes
PRJNA952908 | ENA
TranscriptomicsAnalysis of the transcriptome of adult cardiac myocytes stimulated with CTGF
Transgenic mice with cardiac-restricted overexpression of connective tissue growth factor (CTGF) have substantially increased tolerance towards ischemia/reperfusion injury. In the transgenic mouse model, we found that CTGF induces expression of severeal genes putatively involved in cardioprotection....
ORGANISM(S): Mus musculus 
2015-02-01 | E-GEOD-36073 | biostudies-arrayexpress
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