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GenomicsThe enhancer and promoter landscape of human regulatory and conventional T cell subpopulations
CD4+CD25+FOXP3+ human regulatory T cells (Treg) are essential for self-tolerance and immune homeostasis. Here, we generated genome-wide maps of poised and active enhancer elements marked by histone H3 lysine 4 monomethylation and histone H3 lysine 27 acetylation for CD4+CD25highCD45RA+ naive and CD4...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-43119 | biostudies-arrayexpress
ProteomicsT-cadherin, a major adiponectin binding partner, suppresses ERK signaling in metabolic tissues
T-cadherin, which is a major adiponectin binding partner, exerts various organ-protective effects. However, the specific changes in intracellular signaling that are induced by T-cadherin in metabolic tissues/cells remain unclear. We demonstrated that T-cadherin suppresses ERK signaling in both cultu...
ORGANISM(S): Mus Musculus (mouse) 
2026-02-19 | PXD066195 | JPOST Repository
UnknownT-cell counts in peripheral blood at leukapheresis predict responses to subsequent CAR-T cell therapy.
Not available
S-EPMC9636390 | biostudies-literature
UnknownLangerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells.
Not available
S-EPMC5828466 | biostudies-literature
UnknownConsistent ex vivo cell proliferation during manufacturing predicts favourable outcomes post-CAR-T-cell therapy.
Not available
S-EPMC12436216 | biostudies-literature
UnknownDesmoglein 3-specific CD4+ T cells induce pemphigus vulgaris and interface dermatitis in mice.
Not available
S-EPMC3163963 | biostudies-literature
UnknownAging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals.
Not available
S-EPMC9261342 | biostudies-literature
UnknownHair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma.
Not available
S-EPMC4636445 | biostudies-literature
UnknownImproving function of cytotoxic T-lymphocytes by transforming growth factor-β inhibitor in oral squamous cell carcinoma.
Not available
S-EPMC8486191 | biostudies-literature
UnknownAdiponectin promotes muscle regeneration through binding to T-cadherin.
Not available
S-EPMC6327035 | biostudies-literature
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