Sort   by:  
 Page size 
TranscriptomicsFabT_+or-Tween_S.pyogenesM28_Transcriptomic analysis
We used RNAseq to identify how membrane fatty acid changes might impact and explain the virulence defect during host infection. WT and mFabT expression was compared in THY, and in THY-Tween (as C18:1Δ9 source), which to activates WT FabT repression. RNA isolation and Illumina RNA-seq sequencing: GA...
ORGANISM(S): Streptococcus pyogenes 
2024-09-20 | E-MTAB-14449 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of Daphnia magna exposed to acesulfame K and its photodegradation products against untreated control groups
The experiment investigates how the artificial sweetener acesulfame K and its photodegradation products affect the gene expression in the freshwater invertebrate Daphnia magna. Juvenile D. magna were subjected to an acute immobilization test (OECD Guideline 202) followed by RNA extraction and transc...
ORGANISM(S): Daphnia magna 
2026-09-25 | E-MTAB-17689 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of Danio rerio exposed to acesulfame K and its photodegradation products against untreated control groups
The experiment investigates how the artificial sweetener acesulfame K and its photodegradation products affect the gene expression in the teleost fish Danio rerio. The main test including transcriptomics, was conducted with 10 µg/L and 100 mg/L as test concentrations. Pooled animals from each exposu...
ORGANISM(S): Danio rerio 
2026-09-25 | E-MTAB-17688 | biostudies-arrayexpress
TranscriptomicspiRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans
Transgenerational effects likely have wide-ranging implications for human health, biological adaptation and evolution, however their mechanism and biology remain poorly understood. Here we demonstrate that a germline nuclear small RNA/chromatin pathway can maintain epi-allelic inheritance for many g...
ORGANISM(S): Caenorhabditis elegans 
2012-06-25 | E-GEOD-38813 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of Daphnia magna exposed to abamectin, chlorpyrifos, nicotine, pyriproxyfen and thiacloprid against untreated control groups
The experiment investigates how abamectin, chlorpyrifos, nicotine, pyriproxyfen and thiacloprid affect the gene expression in the freshwater invertebrate Daphnia magna. The experiment aimed to distinguish neurotoxic mechanisms and derive mechanistic information relevant for environmental risk assess...
ORGANISM(S): Daphnia magna 
2026-09-30 | E-MTAB-17707 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of Danio rerio exposed to different concentrations of sucralose against untreated control groups
The experiment investigates how the artificial sweetener sucralose affects gene expression in the teleost fish Danio rerio in order to derive mechanistic information relevant for environmental risk assessment. The main test including transcriptomics, was conducted with 10 µg/L and 100 mg/L as test c...
ORGANISM(S): Danio rerio 
2026-04-30 | E-MTAB-16760 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of Daphnia magna exposed to different concentrations of sucralose against untreated control groups
The experiment investigates how the artificial sweetener sucralose affects behavior and gene expression in the freshwater invertebrate Daphnia magna in order to derive mechanistic information relevant for environmental risk assessment. Juvenile D. magna were first subjected to a behavioral swimming ...
ORGANISM(S): Daphnia magna 
2026-04-30 | E-MTAB-16759 | biostudies-arrayexpress
TranscriptomicsFunction, targets and evolution of Caenorhabditis elegans piRNAs (small RNA-Seq)
piRNAs are required to maintain germline integrity and fertility but their mechanism of action is poorly understood. Here we demonstrate that C. elegans piRNAs silence transcripts in trans through imperfectly complementary sites. We find that target silencing is independent of Piwi endonuclease acti...
ORGANISM(S): Caenorhabditis elegans 
2012-06-18 | E-GEOD-28617 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of Daphnia magna exposed to different concentrations of prochloraz and endosulfan against untreated control groups
The experiment investigates how the azole fungicide prochloraz and the organochlorine insecticide endosulfan affect behavior and gene expression in the freshwater invertebrate Daphnia magna in order to distinguish endocrine from neurotoxic mechanisms and derive mechanistic information relevant for e...
ORGANISM(S): Daphnia magna 
2026-02-28 | E-MTAB-16432 | biostudies-arrayexpress
TranscriptomicsReceptor-independent ectopic activity of PROLACTIN predicts aggressive lung tumors and indicates HDACi-based therapeutic strategies.
Aim: PROLACTIN (PRL), normally produced by the pituitary gland, acts through its receptor (PRL-R) to initiate a signalling cascade to the genome. PRL can also be produced by cancer cells and become oncogenic by stimulating its receptor following an autocrine or paracrine route. Here we investigated ...
ORGANISM(S): Homo sapiens 
2014-08-05 | E-GEOD-49544 | biostudies-arrayexpress
Sort   by:  
 Page size