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GenomicsGenome-wide map of lysine specific demethylase 1 (LSD1) in mouse embryonic stem cells.
We report the identification of LSD1 binding genomic regions in mouse embryonic stem cells (ESC) by high throughput sequencing. By obtaining over 10 million 36 bp reads of sequence from each chromatin immunoprecipitated DNA, we generated genome-wide maps for LSD1 and histone H3 dimethylated on lysin...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-18515 | biostudies-arrayexpress
TranscriptomicsExpression mRNA and miRNA data from human postmortem putamen samples measured using the NanoString nCounter platform
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-77668 | biostudies-arrayexpress
TranscriptomicsExpression mRNA data from human postmortem putamen samples measured using the NanoString nCounter platform
Background: Molecular adaptations in the striatum mediated by dopamine (DA) denervation or Levodopa (L-dopa) treatment have been implicated with the motor deficits found in Parkinson’s disease (PD). Alterations in glutamatergic neurotransmission and anti-oxidant mechanisms are reported to play imp...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-77666 | biostudies-arrayexpress
TranscriptomicsExpression miRNA data from human postmortem putamen samples measured using the NanoString nCounter platform
Background: Molecular adaptations in the striatum mediated by dopamine (DA) denervation or Levodopa (L-dopa) treatment have been implicated with the motor deficits found in Parkinsonâ??s disease (PD). Alterations in glutamatergic neurotransmission and anti-oxidant mechanisms are reported to play imp...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-77667 | biostudies-arrayexpress
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