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TranscriptomicsIntegration of transcriptome and methylome analyses to dissect molecular pathogenesis of primary aldosteronism: comparision between aldosterone-producing adenomas and adjacent adrenal glands
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-05-09 | E-GEOD-60044 | biostudies-arrayexpress
TranscriptomicsMethylation screening of reciprocal genome-wide UPDs identifies novel human specific imprinted genes
Utilizing reciprocal genome-wide uniparental disomy samples presenting with Beckwith-Wiedemann and Silver-Russell syndrome-like phenotypes, we have analyzed ~0.1% of CpG dinucleotides present in the human genome for imprinted differentially methylated regions (DMRs) using the Illumina Infinium Human...
ORGANISM(S): Homo sapiens 
2011-05-26 | E-GEOD-28525 | biostudies-arrayexpress
TranscriptomicsIntegration of transcriptome and methylome analyses to dissect molecular pathogenesis of primary aldosteronism: comparision between aldosterone-producing adenomas and adjacent adrenal glands [methylome]
Primary aldosteronism (PA) is the most common endocrine hypertension comprising 10% of hypertensive patients. A recent series of transcriptome analyses using DNA microarray has shown that neumerous genes are differentially expressed between aldosterone-producing adenoma (APA) and its adjacent adrena...
ORGANISM(S): Homo sapiens 
2015-05-09 | E-GEOD-60043 | biostudies-arrayexpress
TranscriptomicsIntegration of transcriptome and methylome analyses to dissect molecular pathogenesis of primary aldosteronism: comparision between aldosterone-producing adenomas and adjacent adrenal glands [transcriptome]
Primary aldosteronism (PA) is the most common endocrine hypertension comprising 10% of hypertensive patients. A recent series of transcriptome analyses using DNA microarray has shown that neumerous genes are differentially expressed between aldosterone-producing adenoma (APA) and its adjacent adrena...
ORGANISM(S): Homo sapiens 
2015-05-09 | E-GEOD-60042 | biostudies-arrayexpress
TranscriptomicsAn improved method for the isolation of endometrial epithelial and stromal cells from the total hysterectomy specimen
We aimed to improve the efficiency of isolating endometrial epithelial and stromal cells (EMECs and EMSCs) from hysterectomy specimens. We revealed by immunohistochemical staining that the large tissue fragments remaining after collagenase treatment, which are usually discarded after the first filtr...
ORGANISM(S): Homo sapiens 
2016-06-14 | E-GEOD-73090 | biostudies-arrayexpress
TranscriptomicsDNA methyltransferase inhibitor zebularine inhibits human hepatic carcinoma cells proliferation and induces apoptosis.
Hepatocellular carcinoma is one of the most common cancers in world wide. During tumorigenesis, tumor suppressor and cancer-related genes are commonly silenced by aberrant DNA methylation in their promoter regions. Zebularine [1-(β-ᴅ-ribofuranosyl)-1,2-dihydropyrimidin-2-one] acts as an inhibitor of...
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-42490 | biostudies-arrayexpress
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