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TranscriptomicsNovel Lipogenic Enzyme ELOVL7 Involves in Prostate Cancer Growth through Saturated Fatty-acid and Steroid Metabolism
We identified a novel lipogenic gene, ELOVL7, as an over-expressed gene in prostate cancer (PC) cells and it is involved in elongation of long-chain fatty acids and can play some important roles in prostate carcinogenesis. To investigate into downstream pathways of ELOVL7, we performed the gene expr...
ORGANISM(S): Homo sapiens 
2009-04-01 | E-GEOD-14852 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models [Affymetrix]
Cardiovascular complications are the leading cause of death in autosomal dominant polycystic kidney disease (ADPKD), and intracranial aneurysm (ICA) causing subarachnoid hemorrhage is among the most serious complications. The diagnostic and therapeutic strategies for ICAs in ADPKD have not been full...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74452 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models [Agilent]
Cardiovascular complications are the leading cause of death in autosomal dominant polycystic kidney disease (ADPKD), and intracranial aneurysm (ICA) causing subarachnoid hemorrhage is among the most serious complications. The diagnostic and therapeutic strategies for ICAs in ADPKD have not been full...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74451 | biostudies-arrayexpress
ProteomicsRat liver treated by PCN
The combination analyses of transcriptomics, proteomics, phosphoproteomics, and metabolomics in rat liver after repeated oral doses of PXR agonist, PCN, for 7 days were conducted to understand the roles for PXR on non-genotoxic signaling and energy homeostasis. mRNA and proteins in homogenate supern...
ORGANISM(S): Rattus Rattus (black Rat) 
2018-01-01 | PXD006305 | JPOST Repository
ProteomicsHuman tissue microsomed by MRM, MRMHR and SWATH
The purpose of the present study was to examine simultaneously the absolute protein amounts of 152 membrane and membrane-associated proteins, including 30 metabolizing enzymes and 107 transporters, in pooled microsomal fractions of human liver, kidney and intestine by means of SWATH-MS with stable i...
ORGANISM(S): Homo Sapiens (human) 
2018-01-01 | PXD008265 | JPOST Repository
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