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The RNA-induced silencing complex, comprising Argonaute and guide RNA, mediates RNA interference. Here we report the 3.2 Å crystal structure of Kluyveromyces Argonaute (KpAGO) fortuitously complexed with guide RNA originating from small-RNA duplexes autonomously loaded by recombinant KpAGO. Despite ...
ORGANISM(S): Vanderwaltozyma polyspora 
Analysis of synchronized HCT116 cells at various time points up to 10 hours following treatment with DMSO or Nocodazole. Experiment Overall Design: HCT116 colorectal cancer cell line was obtained from the American Type Culture Collection (ATCC) and grown in McCOY’S 5A MEDIUM MODIFIED (SIGMA) with ...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE37723: Degradome sequencing from S. castellii GSE37724: Bacteria-derived small RNAs that co-purify with KpAGO Refer to individual Series
ORGANISM(S): Vanderwaltozyma polyspora 
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