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ProteomicsSecretome identification of immune cell factors mediating metastatic cell homing
Metastatic cell homing is a complex process mediated in part by diffusible factors secreted from immune cells found at a pre-metastatic niche. We report on connecting together secretomics and a TRanscriptional Activity CEll aRray (TRACER) to identify functional paracrine interactions between immune ...
ORGANISM(S): Mus musculus (Mouse) 
2015-12-17 | PXD002051 | Pride
Lc ms/ms Mouse Secretome 
ProteomicsOrthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin enzymes
Protein ubiquitination is mediated sequentially by ubiquitin activating enzyme E1, ubiquitin conjugating enzyme E2, and ubiquitin ligase E3. Uba1 was thought to be the only E1 until the recent identification of Uba6 as an alternative. To differentiate the biological functions of Uba1 and Uba6, we ap...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD005500 | Pride
Lc/ms Ubquitin 
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