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BACKGROUND: Protein undernutrition is prevalent mainly among elderly people, and it could develop diseases such as sarcopenia. Urinary metabolites may become biomarkers reflecting protein undernutrition, but this has been insufficiently investigated.

OBJECTIVE:

2021-05-27 | MTBLS1452 | MetaboLights
Nucleosome assembly protein-1 (NAP-1) is regulator of histone H1 acetylation
NAP - neuroprotective peptide demonstrates increase in neuronal survival when injected into the hippocampus of rats in the model of epilepsy Microarray analysis was used to understand the expression of genes following KA treatment and the changes in gene expression following KA+NAP treatment Keyword...
ORGANISM(S): Rattus norvegicus 
We identified NAP-1 as regulator of histone H1 acetyation.
ORGANISM(S): Drosophila melanogaster 
2020-10-10 | GSE159294 | GEO
Tropolones are small organic compounds with metal-directing moieties. Functionally, tropolones inhibit the proliferation of cancer cell lines, possibly through the inhibition of metalloenzymes such as select histone deacetylases (HDACS). Pan-HDAC inhibitors are therapeutically beneficial in the trea...
ORGANISM(S): Homo sapiens 
2018-01-01 | GSE93099 | GEO
Supporting raw MS data for paper (DOI:10.1083/jcb.202303082) by Paul S. et al., titled "NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis". Index of MS supporting files uploaded: - Related to Figure 6A;S4A (AO3556-AO3579: whole proteome (Unimod: 35; 2016; 4)). -...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-11-01 | MSV000093220 | MassIVE
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