Primary mouse macrophages from wt and PPARD-/- mice, elucidated with thioglycollate, were exposed to PPARbeta/delta specific ligands and the resulting changes in global gene expression were measured.
MDA-MB-231luc1 cells were treated for 6h with PPARbd specific agonists, antagonists and control substances. In addition the influence of PPARbd on gene expression was analyzed via siRNA mediated PPARbd depletion.