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TranscriptomicsMethylation analysis of 12 corresponding pairs of TECs and NECs isolated from human CRC patients with different prognostic TMEs
Methylation analysis of 12 corresponding pairs of tumor endothelial cells (TECs) and normal endothelial cells (NECs) isolated from human colorectal carcinoma (CRC) patients with different prognostic tumor microenvironments (TMEs: Th1-TME vs Control-TME): High and low GBP-1 expression in the tumors d...
ORGANISM(S): Homo sapiens 
2023-05-01 | E-MTAB-10467 | biostudies-arrayexpress
TranscriptomicsGene chip (Clariom S) analysis of 12 corresponding pairs of TECs and NECs from human colorectal carcinoma patients from different prognostic TMEs (Th1-TME vs Control-TME)
Tumor endothelial cells (TECs) and corresponding normal endothelial cells (NECs) were isolated from 12 different human colocrectal carcinoma (CRC) patients with different prognostic tumor microenvironments (TME: Th1-TME vs Control-TME).
ORGANISM(S): Homo sapiens 
2023-05-01 | E-MTAB-10465 | biostudies-arrayexpress
GenomicsClinical exome sequencing of cells freshly isolated from 12 human colorectal carcinoma patients (tumor endothelial cells, normal colon endothelial cells, PBMCs, n=12 each) in comparison to microdisected tumor DNA (n=11) from corresponding FFPE-tissue blocks
Clinical exome sequencing of cells freshly isolated from 12 human colorectal carcinoma patients (tumor endothelial cells, normal colon endothelial cells, PBMCs, each n=12) in comparison to DNA isolated from microdissected tumor cells (n=11) from corresponding FFPE-tissue blocks
ORGANISM(S): Homo sapiens 
2023-05-01 | E-MTAB-10521 | biostudies-arrayexpress
TranscriptomicsIndraccolo_Notch3
Notch3 expression was analyzed in 20 patients suffering from colorectal carcinoma (CRC) and their corresponding colonic normal (NC) tissue.
ORGANISM(S): Homo sapiens 
2011-05-18 | E-MEXP-3188 | biostudies-arrayexpress
TranscriptomicsTEC_GBP-1
Biopsies from patients with colorectal carcinoma were obtained freshly. Two third of the biopsies were used to isolated tumor endothelial cells by collagenase digestion and subsequent CD31-MACS purification. The remaining third of the original biopsy was used to stain immunohistochemically for GBP-1...
ORGANISM(S): Homo sapiens 
2016-10-10 | E-MEXP-3991 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human colorectal carcinoma patients expressing either high or low levels of human guanylate binding protein-1 (GBP-1) to identify coregulated genes
The gene expression profile of 24 human colorectal carcinoma patients either expressing high (n=12) or low (n=12) levels of human guanylate binding protein-1 (GBP-1) were compared in order to identify coregulated genes.
ORGANISM(S): Homo sapiens 
2008-07-31 | E-MEXP-833 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human umbilical vein endothelial cells after transfection with the anti-apoptotic protein vFLIP/K13 of human herpesvirus type-8 (HHV-8)
Modulation of the transcriptome of human umbilical vein endothelial cells (HUVEC) by the anti-apoptotic protein vFLIP/K13 of human herpesvirus type-8 (HHV-8)
ORGANISM(S): Homo sapiens 
2008-11-14 | E-MEXP-1469 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in WT mice and mice lacking PTPN2 in T cells
WT mice and mice lacking PTPN2 in T cells (PTPN2-CD4Cre mice) were treated with AOM/DSS to induce colorectal tumours. RNA was isolated from tumour and non-tumour tissues in the colon. Colon samples from water-treated WT and PTPN2-CD4Cre mice served as additional control. Total RNA was isolated and t...
ORGANISM(S): Mus musculus 
2020-10-03 | E-MTAB-9629 | biostudies-arrayexpress
UnknownPU.1 controls fibroblast polarization and tissue fibrosis.
Not available
S-EPMC6526281 | biostudies-literature
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