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TranscriptomicsContext-specific regulation of monocyte surface IL7R expression and soluble receptor secretion by a common autoimmune risk allele
IL-7 is a key factor in T-cell immunity and IL7R polymorphisms are implicated in susceptibility to autoimmune conditions. IL7R mRNA is induced in stimulated monocytes in a genetically determined manner. The aim this experiment was i) to characterise changes in gene expression with LPS, and ii) post-...
ORGANISM(S): Homo sapiens 
2019-08-17 | E-MTAB-8225 | biostudies-arrayexpress
TranscriptomicsContext-specific regulation of monocyte surface IL7R expression and soluble receptor secretion by a common autoimmune risk allele
IL-7 is a key factor in T-cell immunity and IL7R polymorphisms are implicated in autoimmune pathogenesis. IL7R mRNA is induced in stimulated monocytes in a genetically determined manner. Here we show monocyte surface and soluble IL7R (sIL7R) protein are markedly expressed in response to lipopolysacc...
ORGANISM(S): Homo sapiens 
2019-08-12 | E-MTAB-8207 | biostudies-arrayexpress
UnknownscQCEA: a framework for annotation and quality control report of single-cell RNA-sequencing data.
Not available
S-EPMC10327311 | biostudies-literature
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