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To study the epigenetic regulation of intestinal epithelium we focus on the role of chromatin modulators. Lysine-specific histone demethylase 1a (KDM1A, LSD1) is one of the enzymes that can erase the H3K4me1/2 mark. To assess the role of LSD1 in intestinal epithelium we studied wild type (WT) (Villi...
ORGANISM(S): Mus musculus 
Transcription factors regulate the geneexpression for ordered cellular metabolism, and its change implicated to virulence in several bacterial pathogens including E. coli causing gastroenteritis and colon cancer. Novel transcription regulator NrdR known for regulating ribonucleotide reductase (RNRs)...
ORGANISM(S): Escherichia coli 
2016-06-27 | PXD002705 | Pride
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