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MetabolomicsThe GNMT N-terminus Couples Folate Feedback to Methyl-donor Homeostasis
Maintenance of S-adenosylmethionine (SAM) homeostasis is essential for methylation of biomolecules, nucleotide and polyamine synthesis, and redox balance. While all methyltransferases consume SAM, only a subset of highly tissue specific methyltransferases regulates methylation potential. Among them,...
2026-08-18 | MTBLS15161 | MetaboLights
MetabolomicsTubuloglomerular feedback and salt-sensitive hypertension
Not available
ORGANISM(S): Rattus norvegicus 
ST000757 | MetabolomicsWorkbench
MetabolomicsMetabolic Remodeling of Soil Ecosystems by the medicinal fungus Wolfiporia cocos: Bidirectional Feedback and Functional Consequences
Widely targeted metabolomics based on UPLC-MS/MS was performed to explore metabolic differences between two tissues of Wolfiporia cocos sclerotium. Samples include inner white tissue (Fuling Bai) and outer layer (Fuling Pi) of sclerotium, with 3 biological replicates for each group. A total of 1565 ...
2027-08-10 | MTBLS15360 | MetaboLights
MetabolomicsOxylipin biosynthesis reinforces cellular senescence through a RAS/p53 feedback loop and allows detection of senolysis
Not available
ORGANISM(S): Mus musculus 
ST001708 | MetabolomicsWorkbench
TranscriptomicsDicer and Hsp104 function in a negative feedback loop to confer epigenetic robustness [RNA_correlations]
Epigenetic mechanisms can be influenced by environmental cues and thus evoke phenotypic variation. This plasticity can be advantageous for adaption, but also detrimental if not under tight control. Although having attracted considerable interest, it remains largely unknown if and how environmental c...
ORGANISM(S): Schizosaccharomyces pombe 
2015-04-23 | E-GEOD-60638 | biostudies-arrayexpress
TranscriptomicsDicer and Hsp104 function in a negative feedback loop to confer epigenetic robustness [RNA_profiles]
Epigenetic mechanisms can be influenced by environmental cues and thus evoke phenotypic variation. This plasticity can be advantageous for adaption, but also detrimental if not under tight control. Although having attracted considerable interest, it remains largely unknown if and how environmental c...
ORGANISM(S): Schizosaccharomyces pombe 
2015-04-23 | E-GEOD-60429 | biostudies-arrayexpress
TranscriptomicsDicer and Hsp104 function in a negative feedback loop to confer epigenetic robustness
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Schizosaccharomyces pombe 
2015-04-23 | E-GEOD-60640 | biostudies-arrayexpress
TranscriptomicsGenome-wide MicroRNA Downregulation as a Negative Feedback Mechanism in the Early Phases of Liver Regeneration
Liver is one of the few organs that have the capacity to regenerate in response to injury. We carried out genome-wide miRNA microarray studies during liver regeneration in rats after 70% partial hepatectomy (PH) at early and mid-time points to more thoroughly understand their role. At 3, 12 and 18 h...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-28404 | biostudies-arrayexpress
GenomicsSynthetic negative feedback circuits using engineered small RNAs
Synthetic negative feedback circuits using engineered small RNAs
PRJEB87181 | ENA
ModelsKholodenko2000 - Ultrasensitivity and negative feedback bring oscillations in MAPK cascade
Kholodenko2000 - Ultrasensitivity and negative feedback bring oscillations in MAPK cascade The combination of ultrasensitivity and negative feedback bring sustained oscillations in the mitogen-activated protein kinase cascades. This model is descr...
2024-09-02 | BIOMD0000000010 | BioModels
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