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B lymphopoiesis requires that immunoglobulin genes be accessible to RAG1-RAG2 recombinase. However, the RAG proteins bind widely to open chromatin, which suggests that additional mechanisms must restrict RAG-mediated DNA cleavage. Here we show that developmental downregulation of interleukin 7 (IL-7...
ORGANISM(S): Mus musculus 
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
WTCCC1 project Breast cancer (BC) samples
WTCCC1 project Multiple Sclerosis (MS) samples
WTCCC1 project Ankylosing Spondylitis (AS) samples
WTCCC1 project samples from 1958 British Birth Cohort
WTCCC genome-wide case-control association study for Autoimmune Thyroid Disease (ATD) using the 1958 British Birth Cohort collection as controls.
WTCCC genome-wide case-control association study for Ankylosing Spondylitis (AS) using the 1958 British Birth Cohort collection as controls.
WTCCC genome-wide case-control association study for Multiple Sclerosis (MS) using the 1958 British Birth Cohort collection as controls.
WTCCC genome-wide case-control association study for Breast cancer (BC) using the 1958 British Birth Cohort collection as controls.
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