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TranscriptomicsTranscription profiling of 5 mouse strains liver, kidney and testis to identify the contribution of normal variation and genetic background to mammalian gene expression
5 mouse strains, 3 mice per strain, and 4 microarrays per mouse for a total of 60 microarray experiments. Each sample is liver RNA hybridized against a reference RNA consisting of equal parts mouse liver, kidney, and testis RNA. Two of the 4 microarrays per mouse were done with the experimental sa...
ORGANISM(S): Mus musculus 
2006-02-14 | E-MEXP-568 | biostudies-arrayexpress
TranscriptomicsHepatic xenobiotic metabolizing enzyme gene expression through the life stages of the mouse
Using full-genome arrays, the expression of all XMEs was examined during fetal (gestation day (GD) 19), neonatal (postnatal day (PND) 7), prepubescent (PND30), middle age (12 mon), and old age (18 and 24 mon) in the C57Bl6/J mouse liver and compared to young adults. Fetal and neonatal life stages h...
ORGANISM(S): Mus musculus 
2010-10-01 | E-GEOD-21716 | biostudies-arrayexpress
TranscriptomicsTMPRSS2 Influences Prostate Cancer Metastasis
TMPRSS2 is an androgen-regulated cell surface serine protease expressed predominantly in prostate epithelium. TMPRSS2 is expressed highly in localized high-grade prostate cancers and in the majority of human prostate cancer metastasis. Through the generation of mouse models with a targeted deletion ...
ORGANISM(S): Mus musculus 
2014-09-09 | E-GEOD-58822 | biostudies-arrayexpress
UnknownA cosmopolitan late Ediacaran biotic assemblage: new fossils from Nevada and Namibia support a global biostratigraphic link.
Not available
S-EPMC5524506 | biostudies-literature
UnknownImproved variant discovery through local re-alignment of short-read next-generation sequencing data using SRMA.
Not available
S-EPMC3218665 | biostudies-literature
UnknownBiallelic MADD variants cause a phenotypic spectrum ranging from developmental delay to a multisystem disorder.
Not available
S-EPMC7447524 | biostudies-literature
UnknownAdvances in immune checkpoint inhibitors for bone sarcoma therapy.
Not available
S-EPMC6365405 | biostudies-literature
TranscriptomicsTranscriptome Analysis Predicts Clinical Outcome and Sensitivity to Anticancer Drugs of patients with a Pancreatic Adenocarcinoma
A major impediment to the effective treatment of patients with PDAC (Pancreatic Ductal Adenocarcinoma) is the molecular heterogeneity of the disease, which is reflected in an equally diverse pattern of clinical responses to therapy. We developed an efficient strategy in which PDAC samples from 17 co...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-55513 | biostudies-arrayexpress
UnknownMolecular diagnosis of putative Stargardt Disease probands by exome sequencing.
Not available
S-EPMC3459799 | biostudies-literature
UnknownRecessive ciliopathy mutations in primary endocardial fibroelastosis: a rare neonatal cardiomyopathy in a case of Alstrom syndrome.
Not available
S-EPMC8541947 | biostudies-literature
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