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TranscriptomicsExpression Profiling of Macrophages Reveals Multiple Populations with Distinct Biological Roles in an Immunocompetent Orthotopic Model of Lung Cancer
Macrophages represent an important component of the tumor microenvironment and play a complex role in cancer progression. These cells are characterized by a high degree of plasticity, and alter their phenotype in response to local environmental cues. While the M1/M2 classification of macrophages has...
ORGANISM(S): Mus musculus 
2016-03-02 | E-GEOD-76033 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lung adenocarcinoma and a carcinogen-induced mouse model
Lung tumors
ORGANISM(S): Mus musculus 
2007-07-20 | E-GEOD-2514 | biostudies-arrayexpress
TranscriptomicsTranscriptional imprinting of transmigrating neutrophils on T84 intestinal epithelial cells
Neutrophil accumulation in crypt abscesses is a pathological hallmark of ulcerative colitis. Based on recent evidence that mucosal metabolic changes influence disease outcomes, we hypothesized that transmigrating neutrophils influence the transcriptional profile of intestinal epithelia. Microarray...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-39681 | biostudies-arrayexpress
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